Michelle C Bradley
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Explore the profile of Michelle C Bradley including associated specialties, affiliations and a list of published articles.
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10
Citations
166
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Recent Articles
1.
Ayer A, Fazakerley D, Suarna C, Maghzal G, Sheipouri D, Lee K, et al.
Redox Biol
. 2021 Sep;
46:102127.
PMID: 34521065
Mitochondrial energy production and function rely on optimal concentrations of the essential redox-active lipid, coenzyme Q (CoQ). CoQ deficiency results in mitochondrial dysfunction associated with increased mitochondrial oxidative stress and...
2.
Ong J, Bradley M, Torres J
Cytoskeleton (Hoboken)
. 2020 Dec;
77(12):558-578.
PMID: 33280275
The assembly of the bipolar mitotic spindle requires the careful orchestration of a myriad of enzyme activities like protein posttranslational modifications. Among these, phosphorylation has arisen as the principle mode...
3.
Awad A, Nag A, Pham N, Bradley M, Jabassini N, Nathaniel J, et al.
PLoS One
. 2020 Jun;
15(6):e0234192.
PMID: 32479562
Saccharomyces cerevisiae Coq8 is a member of the ancient UbiB atypical protein kinase family. Coq8, and its orthologs UbiB, ABC1, ADCK3, and ADCK4, are required for the biosynthesis of coenzyme...
4.
Fernandez-Del-Rio L, Kelly M, Contreras J, Bradley M, James A, Murphy M, et al.
Free Radic Biol Med
. 2020 May;
154:105-118.
PMID: 32387128
Coenzyme Q (CoQ) is an essential player in the respiratory electron transport chain and is the only lipid-soluble antioxidant synthesized endogenously in mammalian and yeast cells. In humans, genetic mutations,...
5.
Bradley M, Yang K, Fernandez-Del-Rio L, Ngo J, Ayer A, Tsui H, et al.
J Biol Chem
. 2020 Mar;
295(18):6023-6042.
PMID: 32205446
Coenzyme Q (Q ) is a vital lipid component of the electron transport chain that functions in cellular energy metabolism and as a membrane antioxidant. In the yeast , deletion...
6.
Bernert A, Jacobs E, Reinl S, Choi C, Roberts Buceta P, Culver J, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2019 May;
1864(9):1226-1234.
PMID: 31121262
Terpenoid quinones are liposoluble redox-active compounds that serve as essential electron carriers and antioxidants. One such quinone, rhodoquinone (RQ), couples the respiratory electron transfer chain to the reduction of fumarate...
7.
Tsui H, Pham N, Amer B, Bradley M, Gosschalk J, Gallagher-Jones M, et al.
J Lipid Res
. 2019 May;
60(7):1293-1310.
PMID: 31048406
Coenzyme Q (CoQ or ubiquinone) serves as an essential redox-active lipid in respiratory electron and proton transport during cellular energy metabolism. CoQ also functions as a membrane-localized antioxidant protecting cells...
8.
Eisenberg-Bord M, Tsui H, Antunes D, Fernandez-Del-Rio L, Bradley M, Dunn C, et al.
Contact (Thousand Oaks)
. 2019 Apr;
2:2515256418825409.
PMID: 30937424
Loss of the endoplasmic reticulum (ER)-mitochondria encounter structure (ERMES) complex that resides in contact sites between the yeast ER and mitochondria leads to impaired respiration; however, the reason for that...
9.
Awad A, Bradley M, Fernandez-Del-Rio L, Nag A, Tsui H, Clarke C
Essays Biochem
. 2018 Jul;
62(3):361-376.
PMID: 29980630
Coenzyme Q (ubiquinone or CoQ) is an essential lipid that plays a role in mitochondrial respiratory electron transport and serves as an important antioxidant. In human and yeast cells, CoQ...
10.
Awad A, Venkataramanan S, Nag A, Galivanche A, Bradley M, Neves L, et al.
J Biol Chem
. 2017 Jul;
292(36):14851-14866.
PMID: 28739803
Despite its relatively streamlined genome, there are many important examples of regulated RNA splicing in Here, we report a role for the chromatin remodeler SWI/SNF in respiration, partially via the...