Roland Stocker
Overview
Explore the profile of Roland Stocker including associated specialties, affiliations and a list of published articles.
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Articles
169
Citations
5565
Followers
0
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Recent Articles
1.
Nadel J, Tumanov S, Kong S, Chen W, Giannotti N, Sivasubramaniam V, et al.
JACC Adv
. 2024 Jun;
2(3):100310.
PMID: 38939599
Background: The detection of unstable atherosclerosis remains elusive. Intraplaque myeloperoxidase (MPO) activity causes plaque destabilization in preclinical models, holding promise for clinical translation as a novel imaging biomarker. Objectives: The...
2.
3.
Nadel J, Wang X, Saha P, Bongers A, Tumanov S, Giannotti N, et al.
Eur Heart J Imaging Methods Pract
. 2024 Feb;
2(1):qyae004.
PMID: 38370393
Aims: Unstable atherosclerotic plaques have increased activity of myeloperoxidase (MPO). We examined whether molecular magnetic resonance imaging (MRI) of intraplaque MPO activity predicts future atherothrombosis in rabbits and correlates with...
4.
Li W, Lin A, Hutton M, Dhaliwal H, Nadel J, Rodor J, et al.
bioRxiv
. 2023 Oct;
PMID: 37873248
Atherosclerosis is a chronic inflammatory disease which is driven in part by the aberrant -differentiation of vascular smooth muscle cells (SMCs). No therapeutic drug has been shown to reverse detrimental...
5.
Chen W, Nadel J, Tumanov S, Stocker R
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37445903
Near-infrared autofluorescence (NIRAF) in unstable atherosclerotic plaque has been suggested as a novel imaging technology for high-risk atherosclerosis. Intraplaque hemorrhage (IPH) and bilirubin, derived from the subsequent degradation of heme,...
6.
Lee I, Tumanov S, Wong J, Stocker R, Ho J
iScience
. 2023 Jun;
26(6):106881.
PMID: 37260745
Mass spectrometry (MS)-based untargeted metabolomic and lipidomic approaches are being used increasingly in biomedical research. The adoption and integration of these data are critical to the overall multi-omic toolkit. Recently,...
7.
Nadel J, Giannotti N, Kong S, Ugander M, Jabbour A, Stocker R
J Cardiovasc Comput Tomogr
. 2023 Apr;
17(5):358-360.
PMID: 37032220
No abstract available.
8.
Chen W, Tumanov S, Stanley C, Kong S, Nadel J, Vigder N, et al.
Circ Res
. 2023 Mar;
132(7):812-827.
PMID: 36876485
Background: The rupture of atherosclerotic plaque contributes significantly to cardiovascular disease. Plasma concentrations of bilirubin-a byproduct of heme catabolism-inversely associate with risk of cardiovascular disease, although the link between bilirubin...
9.
Vigder N, Suarna C, Corcilius L, Nadel J, Chen W, Payne R, et al.
Free Radic Biol Med
. 2022 Dec;
195:23-35.
PMID: 36565892
Conversion of the redox probe hydroethidine (HE) to 2-chloroethidium (2-Cl-E) by myeloperoxidase (MPO)-derived hypochlorous acid (HOCl) provides comparable specificity and superior sensitivity to measurement of 3-chlorotyrosine (3-Cl-Tyr), the gold standard...
10.
Chen W, Tumanov S, Kong S, Cheng D, Michaelsson E, Bongers A, et al.
Redox Biol
. 2022 Nov;
58:102532.
PMID: 36375379
Currently there are no established therapies to treat high-risk patients with unstable atherosclerotic lesions that are prone to rupture and can result in thrombosis, abrupt arterial occlusion, and a precipitous...