Michelandrea De Cesare
Overview
Explore the profile of Michelandrea De Cesare including associated specialties, affiliations and a list of published articles.
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63
Citations
958
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Recent Articles
11.
El Bezawy R, De Cesare M, Pennati M, Deraco M, Gandellini P, Zuco V, et al.
J Hematol Oncol
. 2017 Jan;
10(1):19.
PMID: 28100259
Background: The value of microRNAs (miRNAs) as novel targets for cancer therapy is now widely recognized. However, no information is currently available on the expression/functional role of miRNAs in diffuse...
12.
Musso L, Cincinelli R, Zuco V, De Cesare M, Zunino F, Fallacara A, et al.
ChemMedChem
. 2016 Jun;
11(16):1700-4.
PMID: 27311681
A series of compounds containing the N-hydroxyoxindole scaffold were synthesized and evaluated for antitumor activity. The compounds showed potent antiproliferative activity against the wild-type p53 IGROV-1 ovarian carcinoma cell line...
13.
Beretta G, De Cesare M, Albano L, Magnifico A, Carenini N, Corna E, et al.
Tumori
. 2016 Feb;
102(2):144-9.
PMID: 26917410
Purpose: Because the peptidyl-prolyl isomerase PIN1 interacts with multiple protein kinases and phosphoproteins into a network orchestrating the cellular response to various stimuli, there is an increasing interest in exploiting...
14.
Cincinelli R, Zwick V, Musso L, Zuco V, De Cesare M, Zunino F, et al.
Eur J Med Chem
. 2016 Feb;
112:99-105.
PMID: 26890116
Modification of the cap group of biphenylacrylohydroxamic acid-based HDAC inhibitors led to the identification of a new derivative (3) characterized by an indolyl-substituted 4-phenylcinnamic skeleton. Molecular docking was used to...
15.
De Cesare M, Sfondrini L, Pennati M, De Marco C, Motta V, Tagliabue E, et al.
J Transl Med
. 2016 Jan;
14:25.
PMID: 26810896
Background: Diffuse malignant peritoneal mesothelioma (DMPM) is a rare and locally aggressive disease. DMPM prognosis is dismal, mainly due to the lack of effective treatment options and the development of...
16.
De Cesare M, Cominetti D, Doldi V, Lopergolo A, Deraco M, Gandellini P, et al.
Oncotarget
. 2015 May;
6(15):13119-32.
PMID: 25948791
Survivin, which is highly expressed and promotes cell survival in diffuse malignant peritoneal mesothelioma (DMPM), exclusively relies on exportin 1 (XPO1/CRM1) to be shuttled into the cytoplasm and perform its...
17.
Zuco V, De Cesare M, Zaffaroni N, Lanzi C, Cassinelli G
Oncotarget
. 2015 Apr;
6(11):8736-49.
PMID: 25826089
Intrinsic and acquired tumor drug resistance limits the therapeutic efficacy of camptothecins (CPTs). Downregulation of the mitotic kinase PLK1 was found associated with apoptosis induced by SN38 (CPT11 active metabolite)....
18.
Guerrini A, Tesei A, Ferroni C, Paganelli G, Zamagni A, Carloni S, et al.
J Med Chem
. 2014 Aug;
57(17):7263-79.
PMID: 25121586
The androgen receptor (AR) represents the primary target for prostate cancer (PC) treatment even when the disease progresses toward androgen-independent (AIPC) or castration-resistant (CRPC) forms. Because small chemical changes in...
19.
Gatti L, Sevko A, De Cesare M, Arrighetti N, Manenti G, Ciusani E, et al.
Oncotarget
. 2014 Jul;
5(12):4516-28.
PMID: 24980831
Target-specific agents used in melanoma are not curative, and chemokines are being implicated in drug-resistance to target-specific agents. Thus, the use of conventional agents in rationale combinations may result in...
20.
Pennati M, Sbarra S, De Cesare M, Lopergolo A, Locatelli S, Campi E, et al.
Int J Cancer
. 2014 May;
136(2):299-309.
PMID: 24866585
Because available treatments have limited efficacy in triple-negative breast cancer (TNBC), the identification of new therapeutic strategies to improve patients' outcome is urgently needed. In our study, we investigated the...