Michail Shipitsin
Overview
Explore the profile of Michail Shipitsin including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
8413
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0
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Recent Articles
1.
Blume-Jensen P, Berman D, Rimm D, Shipitsin M, Putzi M, Nifong T, et al.
Clin Cancer Res
. 2015 Mar;
21(11):2591-600.
PMID: 25733599
Purpose: Prostate cancer aggressiveness and appropriate therapy are routinely determined following biopsy sampling. Current clinical and pathologic parameters are insufficient for accurate risk prediction leading primarily to overtreatment and also...
2.
Shipitsin M, Small C, Giladi E, Siddiqui S, Choudhury S, Hussain S, et al.
Proteome Sci
. 2014 Jul;
12:40.
PMID: 25075204
Background: We have witnessed significant progress in gene-based approaches to cancer prognostication, promising early intervention for high-risk patients and avoidance of overtreatment for low-risk patients. However, there has been less...
3.
Marotta L, Almendro V, Marusyk A, Shipitsin M, Schemme J, Walker S, et al.
J Clin Invest
. 2011 Jun;
121(7):2723-35.
PMID: 21633165
Intratumor heterogeneity is a major clinical problem because tumor cell subtypes display variable sensitivity to therapeutics and may play different roles in progression. We previously characterized 2 cell populations in...
4.
Maruyama R, Shipitsin M, Choudhury S, Wu Z, Protopopov A, Yao J, et al.
Proc Natl Acad Sci U S A
. 2010 Nov;
109(8):2820-4.
PMID: 21098291
Transcriptome profiling studies suggest that a large fraction of the genome is transcribed and many transcripts function independent of their protein coding potential. The relevance of noncoding RNAs (ncRNAs) in...
5.
Wu Z, Meyer C, Choudhury S, Shipitsin M, Maruyama R, Bessarabova M, et al.
Genome Res
. 2010 Nov;
20(12):1730-9.
PMID: 21045080
We present a powerful application of ultra high-throughput sequencing, SAGE-Seq, for the accurate quantification of normal and neoplastic mammary epithelial cell transcriptomes. We develop data analysis pipelines that allow the...
6.
Park S, Lee H, Li H, Shipitsin M, Gelman R, Polyak K
Clin Cancer Res
. 2010 Jan;
16(3):876-87.
PMID: 20103682
Purpose: To evaluate the expression of stem cell-related markers at the cellular level in human breast tumors of different subtypes and histologic stage. Experimental Design: We performed immunohistochemical analyses of...
7.
Snyder E, Bailey D, Shipitsin M, Polyak K, Loda M
Lab Invest
. 2009 Jun;
89(8):857-66.
PMID: 19488035
Breast carcinoma cells with the CD44+/CD24(low) phenotype have been reported to exhibit 'cancer stem cell' (CSC) characteristics on the basis of their enhanced tumorigenicity and self-renewal potential in immunodeficient mice....
8.
Bloushtain-Qimron N, Yao J, Shipitsin M, Maruyama R, Polyak K
Cell Cycle
. 2009 Feb;
8(6):809-17.
PMID: 19229128
Embryonic stem (ES) cells are pluripotent cells that differentiate into all cell types of the organism. In adult, multipotent tissue-specific stem cells undergo multi-lineage differentiation to preserve normal tissue homeostasis...
9.
Bloushtain-Qimron N, Yao J, Snyder E, Shipitsin M, Campbell L, Mani S, et al.
Proc Natl Acad Sci U S A
. 2008 Sep;
105(37):14076-81.
PMID: 18780791
Cellular identity and differentiation are determined by epigenetic programs. The characteristics of these programs in normal human mammary epithelium and their similarity to those in stem cells are unknown. To...
10.
Mani S, Guo W, Liao M, Eaton E, Ayyanan A, Zhou A, et al.
Cell
. 2008 May;
133(4):704-15.
PMID: 18485877
The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer invasion and metastasis. We here report that the induction of an EMT in immortalized human...