Michael P Washburn
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Explore the profile of Michael P Washburn including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Stewart J, Fleishman N, Staggs V, Thomson M, Stoecklein N, Lawson C, et al.
Children (Basel)
. 2023 Oct;
10(10).
PMID: 37892343
The management of pediatric Peutz-Jeghers Syndrome (PJS) focuses on the prevention of intussusception complicating small intestinal (SI) polyposis. This hinges on the accurate appraisal of the polyp burden to tailor...
12.
Liu X, Zhang Y, Wen Z, Hao Y, Banks C, Lange J, et al.
bioRxiv
. 2023 Feb;
PMID: 36778327
Teaser: In contrast to the SPINDOC/SPIN1 complex, analyses reveal that the WDR76/SPIN1 complex interacts with core histones and is involved in DNA damage.
13.
McCoin C, Franczak E, Washburn M, Sardiu M, Thyfault J
Mol Omics
. 2022 Aug;
18(9):840-852.
PMID: 35929479
Exercise powerfully increases energy metabolism and substrate flux in tissues, a process reliant on dramatic changes in mitochondrial energetics. Liver mitochondria play a multi-factorial role during exercise to fuel hepatic...
14.
Nance K, Thalalla Gamage S, Alam M, Yang A, Levy M, Link C, et al.
Cell Chem Biol
. 2022 Feb;
29(2):312-320.e7.
PMID: 35180432
Synthetic messenger RNA (mRNA) is an emerging therapeutic platform with important applications in oncology and infectious disease. Effective mRNA medicines must be translated by the ribosome but not trigger a...
15.
Zimmermann R, Sardiu M, Manton C, Miah M, Banks C, Adams M, et al.
PLoS One
. 2021 Nov;
16(11):e0259128.
PMID: 34788285
Breast Cancer Metastasis Suppressor 1 (BRMS1) expression is associated with longer patient survival in multiple cancer types. Understanding BRMS1 functionality will provide insights into both mechanism of action and will...
16.
Bhattacharya S, Wang S, Reddy D, Shen S, Zhang Y, Zhang N, et al.
Nat Commun
. 2021 Nov;
12(1):6452.
PMID: 34750379
The RNA recognition motif (RRM) binds to nucleic acids as well as proteins. More than one such domain is found in the pre-mRNA processing hnRNP proteins. While the mode of...
17.
Ooi S, Sato S, Tomomori-Sato C, Zhang Y, Wen Z, Banks C, et al.
Proc Natl Acad Sci U S A
. 2021 Sep;
118(36).
PMID: 34465625
The SNF2 family ATPase Amplified in Liver Cancer 1 (ALC1) is the only chromatin remodeling enzyme with a poly(ADP-ribose) (PAR) binding macrodomain. ALC1 functions together with poly(ADP-ribose) polymerase PARP1 to...
18.
Bhattacharya S, Lange J, Levy M, Florens L, Washburn M, Workman J
J Biol Chem
. 2021 Aug;
297(3):101075.
PMID: 34391778
SETD2 is an important methyltransferase that methylates crucial substrates such as histone H3, tubulin, and STAT1 and also physically interacts with transcription and splicing regulators such as Pol II and...
19.
Zhang P, Zhang Z, Fu Y, Zhang Y, Washburn M, Florens L, et al.
Cell Death Dis
. 2021 Jun;
12(6):608.
PMID: 34117217
Dual specificity tyrosine phosphorylation regulated kinase 1A, DYRK1A, functions in multiple cellular pathways, including signaling, endocytosis, synaptic transmission, and transcription. Alterations in dosage of DYRK1A leads to defects in neurogenesis,...
20.
Bhattacharya S, Levy M, Zhang N, Li H, Florens L, Washburn M, et al.
Nat Commun
. 2021 Mar;
12(1):1443.
PMID: 33664260
Heterogeneous ribonucleoproteins (hnRNPs) are RNA binding molecules that are involved in key processes such as RNA splicing and transcription. One such hnRNP protein, hnRNP L, regulates alternative splicing (AS) by...