Michael Kotliar
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Explore the profile of Michael Kotliar including associated specialties, affiliations and a list of published articles.
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14
Citations
111
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Recent Articles
1.
Kotliar M, Kartashov A, Barski A
Methods Mol Biol
. 2025 Feb;
2880:255-292.
PMID: 39900764
Single-cell (sc) RNA, ATAC, and Multiome sequencing became powerful tools for uncovering biological and disease mechanisms. Unfortunately, manual analysis of sc data presents multiple challenges due to large data volumes...
2.
Lin S, Kotliar M, Vallabh S, Ptasinska A, Assi S, Wunderlich M, et al.
Blood Adv
. 2024 Dec;
9(4):856-861.
PMID: 39705535
No abstract available.
3.
Kotliar M, Cianciolo E, Pham D, Carroll K, Barski A, Jordan M, et al.
bioRxiv
. 2024 Sep;
PMID: 39282257
Article Highlights: Activated beta-cell reactive CD4 and CD8 T effector cells undergo a profound DNA-damage response which is targetable by small molecule inhibitors of the p53 and cell cycle pathways...
4.
Ben-Baruch Morgenstern N, Rochman M, Kotliar M, Dunn J, Mack L, Besse J, et al.
J Allergy Clin Immunol
. 2024 Jun;
154(4):974-987.
PMID: 38871184
Background: Eosinophils are elusive cells involved in allergic inflammation. Single-cell RNA-sequencing (scRNA-seq) is an emerging approach to deeply characterize cellular properties, heterogeneity, and functionality. Objectives: We sought to comprehensively characterize...
5.
Potter S, Zhang L, Kotliar M, Wu Y, Schafer C, Stefan K, et al.
Front Immunol
. 2024 May;
15:1341745.
PMID: 38765012
Individuals with Kabuki syndrome present with immunodeficiency; however, how pathogenic variants in the gene encoding the histone-modifying enzyme lysine methyltransferase 2D (KMT2D) lead to immune alterations remain poorly understood. Following...
6.
Kotliar M, Kartashov A, Barski A
bioRxiv
. 2024 Mar;
PMID: 38464095
Single-cell (sc) RNA, ATAC and Multiome sequencing became powerful tools for uncovering biological and disease mechanisms. Unfortunately, manual analysis of sc data presents multiple challenges due to large data volumes...
7.
Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis
Proper S, Dwyer A, Appiagyei A, Felton J, Ben-Baruch Morgenstern N, Marlman J, et al.
Front Allergy
. 2024 Feb;
5:1323405.
PMID: 38344408
Introduction: Atopic dermatitis (AD) is an allergic skin disease mediated by skin barrier impairment and IL-13-driven immune response. Activation of the aryl hydrocarbon receptor (AHR) has shown promise in early...
8.
Rochman Y, Kotliar M, Ben-Baruch Morgenstern N, Barski A, Wen T, Rothenberg M
Sci Signal
. 2023 Sep;
16(802):eadg6360.
PMID: 37699081
The cytokine thymic stromal lymphopoietin (TSLP) mediates type 2 immune responses, and treatments that interfere with TSLP activity are in clinical use for asthma. Here, we investigated whether TSLP contributes...
9.
Cazares T, Rizvi F, Iyer B, Chen X, Kotliar M, Bejjani A, et al.
PLoS Comput Biol
. 2023 Jan;
19(1):e1010863.
PMID: 36719906
Transcription factors read the genome, fundamentally connecting DNA sequence to gene expression across diverse cell types. Determining how, where, and when TFs bind chromatin will advance our understanding of gene...
10.
Brusilovsky M, Rochman M, Shoda T, Kotliar M, Caldwell J, Mack L, et al.
Gut
. 2022 Aug;
72(5):834-845.
PMID: 35918104
Objective: The contribution of vitamin D (VD) deficiency to the pathogenesis of allergic diseases remains elusive. We aimed to define the impact of VD on oesophageal allergic inflammation. Design: We...