Michael J Watson
Overview
Explore the profile of Michael J Watson including associated specialties, affiliations and a list of published articles.
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22
Citations
421
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Recent Articles
1.
Campbell E, Sazanovich I, Towrie M, Watson M, Lezcano-Gonzalez I, Beale A
J Phys Chem Lett
. 2024 Jun;
15(26):6826-6834.
PMID: 38916593
Resonance Raman spectroscopy can provide insights into complex reaction mechanisms by selectively enhancing the signals of specific molecular species. In this work, we demonstrate that, by changing the excitation wavelength,...
2.
Dosey A, Ellis D, Boyoglu-Barnum S, Syeda H, Saunders M, Watson M, et al.
Cell Rep
. 2023 Dec;
42(12):113553.
PMID: 38096052
The receptor-binding domain (RBD) of influenza virus hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies. Here, we evaluate the ability of several immunofocusing techniques to enhance the functional breadth...
3.
Hale M, Netland J, Chen Y, Thouvenel C, Nabel Smith K, Rich L, et al.
J Exp Med
. 2022 Aug;
219(9).
PMID: 36036783
No abstract available.
4.
Hale M, Netland J, Chen Y, Thouvenel C, Nabel Smith K, Rich L, et al.
J Exp Med
. 2022 Aug;
219(9).
PMID: 35938988
Humoral immunity to SARS-CoV-2 can be supplemented with polyclonal sera from convalescent donors or an engineered monoclonal antibody (mAb) product. While pentameric IgM antibodies are responsible for much of convalescent...
5.
Feng Y, Cai L, Hong W, Zhang C, Tan N, Wang M, et al.
Circulation
. 2022 Apr;
145(22):1663-1683.
PMID: 35400201
Background: Transcriptional reconfiguration is central to heart failure, the most common cause of which is dilated cardiomyopathy (DCM). The effect of 3-dimensional chromatin topology on transcriptional dysregulation and pathogenesis in...
6.
Vorauer C, Wrigley M, Rincon Pabon J, Watson M, Mundorff C, Weis D, et al.
J Am Soc Mass Spectrom
. 2021 May;
32(9):2386-2390.
PMID: 33984240
Hydrogen/deuterium exchange with mass spectrometry (HDX-MS) is a widely used technique to probe protein structural dynamics, track conformational changes, and map protein-protein interactions. Most HDX-MS studies employ a bottom-up approach...
7.
Boyoglu-Barnum S, Ellis D, Gillespie R, Hutchinson G, Park Y, Moin S, et al.
Nature
. 2021 Mar;
592(7855):623-628.
PMID: 33762730
Influenza vaccines that confer broad and durable protection against diverse viral strains would have a major effect on global health, as they would lessen the need for annual vaccine reformulation...
8.
Watson M, Harkewicz R, Hodge E, Vorauer C, Palmer J, Lee K, et al.
J Am Soc Mass Spectrom
. 2020 Dec;
32(2):597-600.
PMID: 33284630
Hydrogen/deuterium exchange with mass spectrometry (HDX-MS) is capable of providing unique insight into complex biological systems that are difficult to study by other techniques. Due to arduous sample handling requirements,...
9.
Butts B, Ahmed M, Bajaj N, Powell P, Pat B, Litovsky S, et al.
JACC Basic Transl Sci
. 2020 Mar;
5(2):109-122.
PMID: 32140620
Increasing left atrial (LA) size predicts outcomes in patients with isolated mitral regurgitation (MR). Chymase is plentiful in the human heart and affects extracellular matrix remodeling. Chymase activation correlates to...
10.
Bishawi M, Roan J, Milano C, Daneshmand M, Schroder J, Chiang Y, et al.
Sci Rep
. 2019 May;
9(1):8029.
PMID: 31142753
Clinically, both percutaneous and surgical approaches to deliver viral vectors to the heart either have resulted in therapeutically inadequate levels of transgene expression or have raised safety concerns associated with...