Robert Tarran
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Explore the profile of Robert Tarran including associated specialties, affiliations and a list of published articles.
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Articles
131
Citations
4375
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Recent Articles
1.
Heinzelmann K, Fysikopoulos A, Jaquin T, Peper-Gabriel J, Hansbauer E, Gruner S, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Nov;
328(1):L75-L92.
PMID: 39499257
Mucus hypersecretion and mucus obstruction are pathogenic features in many chronic lung diseases directly linked to disease severity, exacerbation, progression, and mortality. The Jagged-1/Notch pathway is a promising therapeutic target...
2.
Goriounova A, Sassano M, Wrennall J, Tarran R
Cell Calcium
. 2024 Aug;
123:102945.
PMID: 39191091
Orai1 is a plasma membrane Ca channel involved in store operated calcium entry (SOCE). SOCE can regulate cell growth, exocytosis, gene expression and inflammation. We previously found that short palate...
3.
Bremmer M, Paladino M, Campbell A, Xia K, Tarran R, Hendershot C, et al.
Psychopharmacology (Berl)
. 2024 Aug;
242(2):235-245.
PMID: 39120697
Rationale: Pain and nicotine use are co-occurring conditions with a significant impact on health. Experimental evidence supports an acute analgesic effect of nicotine which may reinforce nicotine use among those...
4.
Hanif S, Au C, Torregroza I, Jannath S, Fabiha T, Bhinder B, et al.
bioRxiv
. 2024 Aug;
PMID: 39091857
G protein-coupled receptors (GPCRs) are the largest class of membrane-bound receptors and transmit critical signals from the extracellular to the intracellular spaces. Transcriptomic data of resected breast tumors shows that...
5.
Pisinger C, Vogelmeier C, Wilson A, Salathe M, Tarran R
Am J Respir Crit Care Med
. 2024 Jul;
210(7):867-868.
PMID: 39078200
No abstract available.
6.
Cholon D, Greenwald M, Higgs M, Quinney N, Boyles S, Meinig S, et al.
Cells
. 2023 Nov;
12(22).
PMID: 37998353
People with cystic fibrosis (pwCF) suffer from chronic and recurring bacterial lung infections that begin very early in life and contribute to progressive lung failure. CF is caused by mutations...
7.
Ahmad S, Wrennall J, Goriounova A, Sekhri M, Iskarpatyoti J, Ghosh A, et al.
Am J Respir Crit Care Med
. 2023 Nov;
209(6):703-715.
PMID: 37972349
Acute respiratory distress syndrome (ARDS) has an unacceptably high mortality rate (35%) and is without effective therapy. Orai1 is a Ca channel involved in store-operated Ca entry (SOCE), a process...
8.
Vukmirovic M, Benam K, Rose J, Turner S, Magin C, Lagares D, et al.
Ann Am Thorac Soc
. 2023 Oct;
21(1):1-11.
PMID: 37903340
"Translational medicine" has been a buzzword for over two decades. The concept was intended to be lofty, to reflect a new "bench-to-bedside" approach to basic and clinical research that would...
9.
Ghosh A, Coakley R, Alexis N, Tarran R
Int J Mol Sci
. 2023 Oct;
24(20).
PMID: 37895029
Proteases such as neutrophil elastase cleave and activate the epithelial sodium channel (ENaC), causing airway dehydration. Our current study explores the impact of increased protease levels in vapers' airways on...
10.
Woodall M, Tarran R, Lee R, Anfishi H, Prins S, Counsell J, et al.
Mol Ther Methods Clin Dev
. 2023 Sep;
30:593-605.
PMID: 37701179
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