Sakthivel Sadayappan
Overview
Explore the profile of Sakthivel Sadayappan including associated specialties, affiliations and a list of published articles.
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174
Citations
4220
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Recent Articles
1.
Wang P, Ahmed M, Nguyen N, Menendez-Montes I, Hsu C, Farag A, et al.
J Clin Invest
. 2025 Feb;
135(4).
PMID: 39959972
Dilated cardiomyopathy (DCM) due to genetic disorders results in decreased myocardial contractility, leading to high morbidity and mortality rates. There are several therapeutic challenges in treating DCM, including poor understanding...
2.
Murugesan S, Saravanakumar L, Sadayappan S, Kannappan R, Sinkey R, Tubinis M, et al.
Am J Physiol Cell Physiol
. 2024 Dec;
328(1):C128-C138.
PMID: 39652412
Women with severe preeclampsia (sPE) exhibit a heightened risk of postpartum cardiovascular disease compared with those with normotensive pregnancies (NTP). Although placental extracellular vesicles (EVs) play a crucial role in...
3.
Desai D, Song T, Singh R, Baby A, McNamara J, Green L, et al.
Cells
. 2024 Nov;
13(22).
PMID: 39594661
, encoding cardiac myosin binding protein-C (cMyBP-C), is the most mutated gene known to cause hypertrophic cardiomyopathy (HCM). However, since little is known about the underlying etiology, additional in vitro...
4.
5.
Mukherjee T, Usman M, Mehdi R, Mendiola E, Ohayon J, Lindquist D, et al.
Comput Biol Med
. 2024 Sep;
181:109065.
PMID: 39217965
The quantification of cardiac strains as structural indices of cardiac function has a growing prevalence in clinical diagnosis. However, the highly heterogeneous four-dimensional (4D) cardiac motion challenges accurate "regional" strain...
6.
Mukherjee T, Usman M, Mehdi R, Mendiola E, Ohayon J, Lindquist D, et al.
bioRxiv
. 2024 Aug;
PMID: 39149320
The quantification of cardiac strains as structural indices of cardiac function has a growing prevalence in clinical diagnosis. However, the highly heterogeneous four-dimensional (4D) cardiac motion challenges accurate "regional" strain...
7.
Desai D, Baby A, Ananthamohan K, Green L, Arif M, Duncan B, et al.
J Mol Cell Cardiol Plus
. 2024 Jul;
8.
PMID: 38957358
Type 2 diabetes mellitus (T2DM) is a metabolic disease and comorbidity associated with several conditions, including cardiac dysfunction leading to heart failure with preserved ejection fraction (HFpEF), in turn resulting...
8.
Ananthamohan K, Brady T, Arif M, Daniels S, Falkner B, Ferguson M, et al.
bioRxiv
. 2024 Jul;
PMID: 38948714
Background: Primary hypertension in childhood tracks into adulthood and may be associated with increased cardiovascular risk. Studies conducted in children and adolescents provide an opportunity to explore the early cardiovascular...
9.
Mukherjee T, Keshavarzian M, Fugate E, Naeini V, Darwish A, Ohayon J, et al.
bioRxiv
. 2024 Jun;
PMID: 38895261
The quantification of cardiac motion using cardiac magnetic resonance imaging (CMR) has shown promise as an early-stage marker for cardiovascular diseases. Despite the growing popularity of CMR-based myocardial strain calculations,...
10.
Jang J, Kim Y, Song T, Park S, Kim H, Koh J, et al.
J Cachexia Sarcopenia Muscle
. 2024 Jun;
15(5):1651-1663.
PMID: 38881251
Background: Loss of muscle strength and endurance with aging or in various conditions negatively affects quality of life. Resistance exercise training (RET) is the most powerful means to improve muscle...