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Michael Francis

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Articles 56
Citations 504
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Recent Articles
1.
Taylor M, Francis M, Choi C
Biomedicines . 2025 Jan; 12(12. PMID: 39767806
Background: Small conductance Ca activated K channels (K2.3) are important regulators of vascular function. They provide Ca-dependent hyperpolarization of the endothelial membrane potential, promoting agonist-induced vasodilation. Another important mechanism of...
2.
Gorman B, Ji S, Francis M, Sendamarai A, Shi Y, Devineni P, et al.
Nat Commun . 2024 Oct; 15(1):8629. PMID: 39366959
Lung cancer remains the leading cause of cancer mortality, despite declining smoking rates. Previous lung cancer GWAS have identified numerous loci, but separating the genetic risks of lung cancer and...
3.
Webster A, Francis M, Gribble H, Griffin C, Hafeez S, Hansen V, et al.
Radiother Oncol . 2024 Jul; 199:110460. PMID: 39069085
Background And Purpose: Radiotherapy trial quality assurance (RT QA) is crucial for ensuring the safe and reliable delivery of radiotherapy trials, and minimizing inter-institutional variations. While previous studies focused on...
4.
Francis M, Westerman K, Manning A, Ye K
PLoS Genet . 2024 Jul; 20(7):e1011288. PMID: 38990837
We examined the associations of vegetarianism with metabolic biomarkers using traditional and genetic epidemiology. First, we addressed inconsistencies in self-reported vegetarianism among UK Biobank participants by utilizing data from two...
5.
Gorman B, Francis M, Nealon C, Halladay C, Duro N, Markianos K, et al.
Commun Biol . 2024 Apr; 7(1):418. PMID: 38582945
Fuchs endothelial corneal dystrophy (FECD) is a leading indication for corneal transplantation, but its molecular etiology remains poorly understood. We performed genome-wide association studies (GWAS) of FECD in the Million...
6.
Sheean A, Francis M
Arthroscopy . 2024 Jan; 40(4):1105-1107. PMID: 38219093
Rates of rotator cuff repair retear remain unacceptably high and are frequently the source of diminished shoulder function and patient dissatisfaction. Endocrinopathies have been implicated in these processes. Parathyroid hormone...
7.
Xu H, Sun Y, Francis M, Cheng C, Modulla N, Brenna J, et al.
medRxiv . 2023 Oct; PMID: 37873425
The neural tissue is rich in polyunsaturated fatty acids (PUFAs), components that are indispensable for the proper functioning of neurons, such as neurotransmission. PUFA nutritional deficiency and imbalance have been...
8.
Rolle M, Williams A, Boeykens A, Garba D, McLellan R, Francis M, et al.
World Neurosurg . 2023 Aug; 179:e150-e159. PMID: 37597663
Background: The neurosurgical workforce in the Caribbean and surrounding countries is largely unknown due to the diversity in cultural, linguistic, political, financial disparities, and colonial history between the countries. About...
9.
Peachey N, Gorman B, Francis M, Nealon C, Halladay C, Duro N, et al.
Res Sq . 2023 May; PMID: 37205546
Fuchs endothelial corneal dystrophy (FECD) is a leading indication for corneal transplantation, but its molecular pathophysiology remains poorly understood. We performed genome-wide association studies (GWAS) of FECD in the Million...
10.
Francis M, Li C, Sun Y, Zhou J, Li X, Brenna J, et al.
PLoS Genet . 2023 Apr; 19(4):e1010735. PMID: 37071599
[This corrects the article DOI: 10.1371/journal.pgen.1009431.].