Troy Stevens
Overview
Explore the profile of Troy Stevens including associated specialties, affiliations and a list of published articles.
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Articles
118
Citations
3007
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Recent Articles
1.
Stone M, Choi C, Dey N, Swain G, Stevens T, Sayner S
Am J Physiol Lung Cell Mol Physiol
. 2024 Sep;
327(5):L756-L768.
PMID: 39316682
Type three secretion system (TTSS)-competent Pseudomonas aeruginosa expressing soluble promiscuous cyclase, exoenzyme Y (ExoY), generates cyclic nucleotides in pulmonary microvascular endothelial cells (PMVECs). Within cells, cyclic nucleotide signals are highly...
2.
Hough R, Alvira C, Bastarache J, Erzurum S, Kuebler W, Schmidt E, et al.
Am J Respir Cell Mol Biol
. 2024 Aug;
71(4):388-406.
PMID: 39189891
Lung endothelium resides at the interface between the circulation and the underlying tissue, where it senses biochemical and mechanical properties of both the blood as it flows through the vascular...
3.
deWeever A, Paudel S, Zhou C, Francis C, Tambe D, Frank D, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Jul;
327(3):L395-L405.
PMID: 39076085
utilizes a type 3 secretion system to intoxicate host cells with the nucleotidyl cyclase ExoY. After activation by its host cell cofactor, filamentous actin, ExoY produces purine and pyrimidine cyclic...
4.
Zhang Q, Yaoita N, Tabuchi A, Liu S, Chen S, Li Q, et al.
Circulation
. 2024 Jun;
150(6):466-487.
PMID: 38873770
Background: Endothelial cell (EC) apoptosis and proliferation of apoptosis-resistant cells is a hallmark of pulmonary hypertension (PH). Yet, why some ECs die and others proliferate and how this contributes to...
5.
Palakshappa J, Batt J, Bodine S, Connolly B, Doles J, Falvey J, et al.
Am J Respir Crit Care Med
. 2024 Mar;
209(11):1304-1313.
PMID: 38477657
Acute respiratory distress syndrome (ARDS) is associated with long-term impairments in brain and muscle function that significantly impact the quality of life of those who survive the acute illness. The...
6.
Renema P, Pittet J, Brandon A, Leal Jr S, Gu S, Promer G, et al.
PLoS One
. 2024 Feb;
19(2):e0298816.
PMID: 38394060
Background: Bacterial pneumonia and sepsis are both common causes of end-organ dysfunction, especially in immunocompromised and critically ill patients. Pre-clinical data demonstrate that bacterial pneumonia and sepsis elicit the production...
7.
Singh N, Eickhoff C, Garcia-Agundez A, Bertone P, Paudel S, Tambe D, et al.
Sci Rep
. 2023 Dec;
13(1):22534.
PMID: 38110438
Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can...
8.
Balczon R, Lin M, Voth S, Nelson A, Schupp J, Wagener B, et al.
Physiol Rev
. 2023 Aug;
104(2):533-587.
PMID: 37561137
Lung endothelia in the arteries, capillaries, and veins are heterogeneous in structure and function. Lung capillaries in particular represent a unique vascular niche, with a thin yet highly restrictive alveolar-capillary...
9.
Stevens R, Lee J, Bauer N, Stevens T
Am J Respir Cell Mol Biol
. 2023 Jul;
69(4):380-382.
PMID: 37478332
No abstract available.
10.
Gwin M, Alexeyev M, Geurts A, Lee J, Zhou C, Yang X, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Jun;
325(2):L174-L189.
PMID: 37366533
Pneumonia elicits the production of cytotoxic beta amyloid (Aβ) that contributes to end-organ dysfunction, yet the mechanism(s) linking infection to activation of the amyloidogenic pathway that produces cytotoxic Aβ is...