Michael C ODonovan
Overview
Explore the profile of Michael C ODonovan including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
358
Citations
29637
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Schipper M, de Leeuw C, Maciel B, Wightman D, Hubers N, Boomsma D, et al.
Nat Genet
. 2025 Feb;
57(2):323-333.
PMID: 39930082
Genome-wide association studies (GWAS) yield large numbers of genetic loci associated with traits and diseases. Predicting the effector genes that mediate these locus-trait associations remains challenging. Here we present the...
2.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
3.
Panagiotaropoulou G, Georgii Hellberg K, Coleman J, Seok D, Kalman J, Mitchell P, et al.
Br J Psychiatry
. 2025 Jan;
1-12.
PMID: 39806801
Background: Accurate diagnosis of bipolar disorder (BPD) is difficult in clinical practice, with an average delay between symptom onset and diagnosis of about 7 years. A depressive episode often precedes...
4.
Woolway G, Legge S, Lynham A, Smart S, Hubbard L, Daniel E, et al.
Schizophrenia (Heidelb)
. 2024 Oct;
10(1):99.
PMID: 39477999
The increasing availability of biobanks is changing the way individuals are identified for genomic research. This study assesses the validity of a self-reported clinical diagnosis of schizophrenia. The study included...
5.
Dempster E, Wong C, Burrage J, Hannon E, Quattrone D, Trotta G, et al.
Mol Psychiatry
. 2024 Oct;
PMID: 39406996
The rising prevalence and legalisation of cannabis worldwide have underscored the need for a comprehensive understanding of its biological impact, particularly on mental health. Epigenetic mechanisms, specifically DNA methylation, have...
6.
Smart S, Legge S, Fenner E, Pardinas A, Woolway G, Lynham A, et al.
medRxiv
. 2024 Oct;
PMID: 39371177
The missense SNP NC_000004.12:g.102267552C>T (SLC39A8.p.(Ala391Thr), rs13107325) in , which encodes a zinc transporter, has been linked to schizophrenia and is the likely causal variant for one of the genome-wide association...
7.
Yuan K, Longchamps R, Pardinas A, Yu M, Chen T, Lin S, et al.
Nat Genet
. 2024 Aug;
56(9):1841-1850.
PMID: 39187616
Genome-wide association studies (GWAS) of human complex traits or diseases often implicate genetic loci that span hundreds or thousands of genetic variants, many of which have similar statistical significance. While...
8.
Tume C, Chick S, Holmans P, Rees E, ODonovan M, Cameron D, et al.
Biol Psychiatry Glob Open Sci
. 2024 Aug;
4(5):100345.
PMID: 39099730
Background: The prefrontal cortex (PFC) has been strongly implicated in the pathophysiology of schizophrenia. Here, we combined high-resolution single-nuclei RNA sequencing data from the human PFC with large-scale genomic data...
9.
Cameron D, Vinh N, Prapaiwongs P, Perry E, Walters J, Li M, et al.
Schizophr Bull
. 2024 Jun;
50(5):1171-1184.
PMID: 38869145
Background: The ganglionic eminences (GE) are fetal-specific structures that give rise to gamma-aminobutyric acid (GABA)- and acetylcholine-releasing neurons of the forebrain. Given the evidence for GABAergic, cholinergic, and neurodevelopmental disturbances...
10.
Caseras X, Simmonds E, Pardinas A, Anney R, Legge S, Walters J, et al.
Transl Psychiatry
. 2024 Apr;
14(1):194.
PMID: 38649377
Recent research has highlighted the role of complement genes in shaping the microstructure of the brain during early development, and in contributing to common allele risk for Schizophrenia. We hypothesised...