Patrick F Sullivan
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Explore the profile of Patrick F Sullivan including associated specialties, affiliations and a list of published articles.
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433
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44808
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Recent Articles
1.
Nguyen T, Meijsen J, Sigstrom R, Kuja-Halkola R, Xiong Y, Harder A, et al.
EBioMedicine
. 2025 Jan;
112:105576.
PMID: 39889373
Background: Psychotic major depressive disorder (MDD), a subtype of MDD characterised by psychotic symptoms that occur exclusively during mood episode, is clinically significant yet underexplored genetically due to its rarity....
2.
Jiang Z, Sullivan P, Li T, Zhao B, Wang X, Luo T, et al.
Sci Adv
. 2025 Jan;
11(4):eadq5360.
PMID: 39854466
Genes on the X chromosome are extensively expressed in the human brain. However, little is known for the X chromosome's impact on the brain anatomy, microstructure, and functional networks. We...
3.
Lee S, McAfee J, Lee J, Gomez A, Ledford A, Clarke D, et al.
Cell
. 2025 Jan;
188(5):1409-1424.e21.
PMID: 39848247
A meta-genome-wide association study across eight psychiatric disorders has highlighted the genetic architecture of pleiotropy in major psychiatric disorders. However, mechanisms underlying pleiotropic effects of the associated variants remain to...
4.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
5.
Yao S, Harder A, Darki F, Chang Y, Li A, Nikouei K, et al.
Nat Commun
. 2025 Jan;
16(1):395.
PMID: 39755698
Identifying cell types and brain regions critical for psychiatric disorders and brain traits is essential for targeted neurobiological research. By integrating genomic insights from genome-wide association studies with a comprehensive...
6.
Fan Y, Chen J, Fan Z, Chirinos J, Stein J, Sullivan P, et al.
medRxiv
. 2024 Nov;
PMID: 39606337
Human organ structure and function are important endophenotypes for clinical outcomes. Genome-wide association studies (GWAS) have identified numerous common variants associated with phenotypes derived from magnetic resonance imaging (MRI) of...
7.
Walker A, Karlsson R, Szatkiewicz J, Thornton L, Yilmaz Z, Leppa V, et al.
Mol Psychiatry
. 2024 Nov;
PMID: 39533101
This study represents the first large-scale investigation of rare (<1% population frequency) copy number variants (CNVs) in anorexia nervosa (AN). Large, rare CNVs are reported to be causally associated with...
8.
Barker M, Koiv K, Magnusdottir I, Milbourn H, Wang B, Du X, et al.
Nat Commun
. 2024 Sep;
15(1):8124.
PMID: 39327436
Individuals with mental illness are at higher risk of severe COVID-19 outcomes. However, previous studies on the uptake of COVID-19 vaccination in this population have reported conflicting results. Using data...
9.
Bergstedt J, Pasman J, Ma Z, Harder A, Yao S, Parker N, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(6):754-769.
PMID: 39215135
Major depressive disorder (MDD) and cardiovascular disease (CVD) are often comorbid, resulting in excess morbidity and mortality. Here we show that CVDs share most of their genetic risk factors with...
10.
Song J, Pasman J, Johansson V, Kuja-Halkola R, Harder A, Karlsson R, et al.
JAMA Psychiatry
. 2024 Aug;
81(12):1246-1252.
PMID: 39196586
Importance: Schizophrenia and bipolar disorder are highly heritable psychiatric disorders with strong genetic and phenotypic overlap. Twin and molecular methods can be leveraged to predict the shared genetic liability to...