Matthias Stadtfeld
Overview
Explore the profile of Matthias Stadtfeld including associated specialties, affiliations and a list of published articles.
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53
Citations
7011
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Recent Articles
21.
Wu T, Liu Y, Wen D, Tseng Z, Tahmasian M, Zhong M, et al.
Cell Stem Cell
. 2014 Sep;
15(3):281-294.
PMID: 25192463
For future application of induced pluripotent stem cell (iPSC) technology, the ability to assess the overall quality of iPSC clones will be an important issue. Here we show that the...
22.
West J, Cook A, Alver B, Stadtfeld M, Deaton A, Hochedlinger K, et al.
Nat Commun
. 2014 Aug;
5:4719.
PMID: 25158628
Chromatin structure determines DNA accessibility. We compare nucleosome occupancy in mouse and human embryonic stem cells (ESCs), induced-pluripotent stem cells (iPSCs) and differentiated cell types using MNase-seq. To address variability...
23.
24.
Apostolou E, Ferrari F, Walsh R, Bar-Nur O, Stadtfeld M, Cheloufi S, et al.
Cell Stem Cell
. 2013 May;
12(6):699-712.
PMID: 23665121
The chromatin state of pluripotency genes has been studied extensively in embryonic stem cells (ESCs) and differentiated cells, but their potential interactions with other parts of the genome remain largely...
25.
Gonzalez F, Georgieva D, Vanoli F, Shi Z, Stadtfeld M, Ludwig T, et al.
Cell Rep
. 2013 Mar;
3(3):651-60.
PMID: 23478019
Induced pluripotent stem cells (iPSCs) hold great promise for personalized regenerative medicine. However, recent studies show that iPSC lines carry genetic abnormalities, suggesting that reprogramming may be mutagenic. Here, we...
26.
Polo J, Anderssen E, Walsh R, Schwarz B, Nefzger C, Lim S, et al.
Cell
. 2012 Dec;
151(7):1617-32.
PMID: 23260147
Factor-induced reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is inefficient, complicating mechanistic studies. Here, we examined defined intermediate cell populations poised to becoming iPSCs by genome-wide analyses....
27.
Buckley S, Aranda-Orgilles B, Strikoudis A, Apostolou E, Loizou E, Moran-Crusio K, et al.
Cell Stem Cell
. 2012 Oct;
11(6):783-98.
PMID: 23103054
Although transcriptional regulation of stem cell pluripotency and differentiation has been extensively studied, only a small number of studies have addressed the roles for posttranslational modifications in these processes. A...
28.
29.
Stadtfeld M, Apostolou E, Ferrari F, Choi J, Walsh R, Chen T, et al.
Nat Genet
. 2012 Mar;
44(4):398-405, S1-2.
PMID: 22387999
The generation of induced pluripotent stem cells (iPSCs) often results in aberrant epigenetic silencing of the imprinted Dlk1-Dio3 gene cluster, compromising the ability to generate entirely iPSC-derived adult mice ('all-iPSC...
30.
Stadtfeld M, Hochedlinger K
Genes Dev
. 2010 Oct;
24(20):2239-63.
PMID: 20952534
The generation of induced pluripotent stem cells (iPSCs) from somatic cells demonstrated that adult mammalian cells can be reprogrammed to a pluripotent state by the enforced expression of a few...