Matthias Stadtfeld
Overview
Explore the profile of Matthias Stadtfeld including associated specialties, affiliations and a list of published articles.
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7011
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Recent Articles
11.
Apostolou E, Stadtfeld M
Curr Opin Genet Dev
. 2018 Jun;
52:77-85.
PMID: 29925040
The discovery of induced pluripotent stem cells (iPSCs) has solidified the concept of transcription factors as major players in controlling cell identity and provided a tractable tool to study how...
12.
Amlani B, Liu Y, Chen T, Ee L, Lopez P, Heguy A, et al.
Cell Rep
. 2018 Feb;
22(4):876-884.
PMID: 29420174
The ability of induced pluripotent stem cells (iPSCs) to differentiate into all adult cell types makes them attractive for research and regenerative medicine; however, it remains unknown when and how...
13.
Donato V, Bonora M, Simoneschi D, Sartini D, Kudo Y, Saraf A, et al.
Nat Cell Biol
. 2017 Mar;
19(4):341-351.
PMID: 28319092
Self-renewing naive mouse embryonic stem cells (mESCs) contain few mitochondria, which increase in number and volume at the onset of differentiation. KBP (encoded by Kif1bp) is an interactor of the...
14.
Liu L, Brumbaugh J, Bar-Nur O, Smith Z, Stadtfeld M, Meissner A, et al.
Cell Rep
. 2016 Dec;
17(12):3395-3406.
PMID: 28009305
Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is typically an inefficient and asynchronous process. A variety of technological efforts have been made to accelerate and/or synchronize this...
15.
Strikoudis A, Lazaris C, Trimarchi T, Galvao Neto A, Yang Y, Ntziachristos P, et al.
Nat Cell Biol
. 2016 Oct;
18(11):1127-1138.
PMID: 27749823
Pluripotent embryonic stem cells (ESCs) self-renew or differentiate into all tissues of the developing embryo and cell-specification factors are necessary to balance gene expression. Here we delineate the function of...
16.
Swanzey E, Stadtfeld M
Development
. 2016 Oct;
143(22):4161-4166.
PMID: 27729406
Genomic imprinting results in the monoallelic expression of genes that encode important regulators of growth and proliferation. Dysregulation of imprinted genes, such as those within the Dlk1-Dio3 locus, is associated...
17.
Tu S, Narendra V, Yamaji M, Vidal S, Rojas L, Wang X, et al.
Nature
. 2016 Jun;
534(7607):387-90.
PMID: 27281218
Developmental specification of germ cells lies at the heart of inheritance, as germ cells contain all of the genetic and epigenetic information transmitted between generations. The critical developmental event distinguishing...
18.
Cheloufi S, Elling U, Hopfgartner B, Jung Y, Murn J, Ninova M, et al.
Nature
. 2015 Dec;
528(7581):218-24.
PMID: 26659182
Cellular differentiation involves profound remodelling of chromatic landscapes, yet the mechanisms by which somatic cell identity is subsequently maintained remain incompletely understood. To further elucidate regulatory pathways that safeguard the...
19.
Vidal S, Stadtfeld M, Apostolou E
Cell Stem Cell
. 2015 Jan;
16(1):9-10.
PMID: 25575077
A series of five related publications describe an alternative pluripotent state that is dependent on continuous high levels of exogenous reprogramming factor expression. A comprehensive effort to molecularly compare the...
20.
Vidal S, Amlani B, Chen T, Tsirigos A, Stadtfeld M
Stem Cell Reports
. 2014 Nov;
3(4):574-84.
PMID: 25358786
The differentiated state of somatic cells provides barriers for the derivation of induced pluripotent stem cells (iPSCs). To address why some cell types reprogram more readily than others, we studied...