» Authors » Matthew S Wilken

Matthew S Wilken

Explore the profile of Matthew S Wilken including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 18
Citations 2505
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
11.
Ueki Y, Wilken M, Cox K, Chipman L, Bermingham-McDonogh O, Reh T
Development . 2015 Jan; 142(3):533-43. PMID: 25605781
The primary glial cells in the retina, the Müller glia, differentiate from retinal progenitors in the first postnatal week. CNTF/LIF/STAT3 signaling has been shown to promote their differentiation; however, another...
12.
Vierstra J, Rynes E, Sandstrom R, Zhang M, Canfield T, Hansen R, et al.
Science . 2014 Nov; 346(6212):1007-12. PMID: 25411453
To study the evolutionary dynamics of regulatory DNA, we mapped >1.3 million deoxyribonuclease I-hypersensitive sites (DHSs) in 45 mouse cell and tissue types, and systematically compared these with human DHS...
13.
Stergachis A, Neph S, Sandstrom R, Haugen E, Reynolds A, Zhang M, et al.
Nature . 2014 Nov; 515(7527):365-70. PMID: 25409825
The basic body plan and major physiological axes have been highly conserved during mammalian evolution, yet only a small fraction of the human genome sequence appears to be subject to...
14.
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, et al.
Nature . 2014 Nov; 515(7527):355-64. PMID: 25409824
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To...
15.
Pollak J, Wilken M, Ueki Y, Cox K, Sullivan J, Taylor R, et al.
Development . 2013 May; 140(12):2619-31. PMID: 23637330
Non-mammalian vertebrates have a robust ability to regenerate injured retinal neurons from Müller glia (MG) that activate the gene encoding the proneural factor Achaete-scute homolog 1 (Ascl1; also known as...
16.
Ueki Y, Karl M, Sudar S, Pollak J, Taylor R, Loeffler K, et al.
Glia . 2012 Jul; 60(10):1579-89. PMID: 22777914
Müller glia are normally mitotically quiescent cells, but in certain pathological states they can re-enter the mitotic cell cycle. While several cell cycle regulators have been shown to be important...
17.
McCaughtry T, Baldwin T, Wilken M, Hogquist K
J Exp Med . 2008 Oct; 205(11):2575-84. PMID: 18936237
The thymic medulla is generally held to be a specialized environment for negative selection. However, many self-reactive thymocytes first encounter ubiquitous self-antigens in the cortex. Cortical epithelial cells are vital...
18.
McCaughtry T, Wilken M, Hogquist K
J Exp Med . 2007 Oct; 204(11):2513-20. PMID: 17908937
Conventional alphabeta T cell precursors undergo positive selection in the thymic cortex. When this is successful, they migrate to the medulla and are exposed to tissue-specific antigens (TSA) for purposes...