Matthew P McCormack
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Explore the profile of Matthew P McCormack including associated specialties, affiliations and a list of published articles.
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32
Citations
691
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Recent Articles
1.
Tremblay C, Saw J, Yan F, Boyle J, Amarasinghe O, Abdollahi S, et al.
Leukemia
. 2025 Jan;
39(3):577-589.
PMID: 39849166
Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) is an immature subtype of T-cell acute lymphoblastic leukemia (T-ALL) commonly show deregulation of the LMO2-LYL1 stem cell transcription factors, activating mutations of...
2.
Gao M, Georgiou A, Lin V, Jahja M, White C, Anderson M, et al.
Br J Haematol
. 2024 Jul;
205(4):1389-1394.
PMID: 39031781
Despite significant progress in treating chronic lymphocytic leukaemia (CLL), resistance to therapy remains challenging. NOTCH1 activation, common in CLL, confers adverse prognosis. This study explores the impact of NOTCH1 signalling...
3.
Jackson J, Nutt S, McCormack M
Front Immunol
. 2023 Jul;
14:1197490.
PMID: 37398663
The Haematopoietically expressed homeobox transcription factor (Hhex) is a transcriptional repressor that is of fundamental importance across species, as evident by its evolutionary conservation spanning fish, amphibians, birds, mice and...
4.
Abdulla H, Alserihi R, Flensburg C, Abeysekera W, Luo M, Gray D, et al.
J Exp Med
. 2023 Mar;
220(6).
PMID: 36920307
Cell competition has recently emerged as an important tumor suppressor mechanism in the thymus that inhibits autonomous thymic maintenance. Here, we show that the oncogenic transcription factor Lmo2 causes autonomous...
5.
6.
Abdulla H, Vo A, Shields B, Davies T, Jackson J, Alserihi R, et al.
Leukemia
. 2021 Jan;
35(8):2205-2219.
PMID: 33483615
The majority of cases of T-cell acute lymphoblastic leukemia (T-ALL) contain chromosomal abnormalities that drive overexpression of oncogenic transcription factors. However, whether these initiating oncogenes are required for leukemia maintenance...
7.
Goh W, Scheer S, Jackson J, Hediyeh-Zadeh S, Delconte R, Schuster I, et al.
Cell Rep
. 2020 Oct;
33(3):108285.
PMID: 33086067
Hhex encodes a homeobox transcriptional regulator important for embryonic development and hematopoiesis. Hhex is highly expressed in NK cells, and its germline deletion results in significant defects in lymphoid development,...
8.
Amann-Zalcenstein D, Tian L, Schreuder J, Tomei S, Lin D, Fairfax K, et al.
Nat Immunol
. 2020 Oct;
21(12):1574-1584.
PMID: 33077975
A classical view of blood cell development is that multipotent hematopoietic stem and progenitor cells (HSPCs) become lineage-restricted at defined stages. Linc-KitSca-1Flt3 cells, termed lymphoid-primed multipotent progenitors (LMPPs), have lost...
9.
Carmichael C, Wang J, Nguyen T, Kolawole O, Benyoucef A, De Maziere C, et al.
Blood
. 2020 May;
136(8):957-973.
PMID: 32369597
Modulators of epithelial-to-mesenchymal transition (EMT) have recently emerged as novel players in the field of leukemia biology. The mechanisms by which EMT modulators contribute to leukemia pathogenesis, however, remain to...
10.
McManus J, Nguyen N, Davey R, MacLean H, Pomilio G, McCormack M, et al.
Eur J Haematol
. 2020 Apr;
105(3):247-254.
PMID: 32311143
Background: Androgens function through DNA and non-DNA binding-dependent signalling of the androgen receptor (AR). How androgens promote erythropoiesis is not fully understood. Design And Methods: To identify the androgen signalling...