Matthew A Mitsche
Overview
Explore the profile of Matthew A Mitsche including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
638
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Moore M, Wang X, Kennelly J, Shi H, Ishino Y, Kano K, et al.
Hepatology
. 2024 May;
81(2):576-590.
PMID: 38776184
Background And Aims: The common genetic variant rs641738 C>T is a risk factor for metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis (MASH), including liver fibrosis, and is associated...
2.
Fu X, Deja S, Fletcher J, Anderson N, Mizerska M, Vale G, et al.
Nat Commun
. 2021 Jun;
12(1):3756.
PMID: 34145255
De novo lipogenesis (DNL) is disrupted in a wide range of human disease. Thus, quantification of DNL may provide insight into mechanisms and guide interventions if it can be performed...
3.
Xia M, Chandrasekaran P, Rong S, Fu X, Mitsche M
J Lipid Res
. 2020 Aug;
62:100031.
PMID: 32859645
Genetic variants that increase the risk of fatty liver disease and cirrhosis have recently been identified in the proximity of membrane-bound O-acyltransferase domain-containing 7 (MBOAT7). To elucidate the link between...
4.
Chimalapati S, Santos M, Lafrance A, Ray A, Lee W, Rivera-Cancel G, et al.
Elife
. 2020 Aug;
9.
PMID: 32808593
Pathogens find diverse niches for survival including inside a host cell where replication occurs in a relatively protective environment. is a facultative intracellular pathogen that uses its type 3 secretion...
5.
Cardoso A, Lam N, Savla J, Nakada Y, Pereira A, Elnwasany A, et al.
Nat Metab
. 2020 Jul;
2(2):167-178.
PMID: 32617517
The neonatal mammalian heart is capable of regeneration for a brief window of time after birth. However, this regenerative capacity is lost within the first week of life, which coincides...
6.
Theodoropoulos P, Wang W, Budhipramono A, Thompson B, Madhusudhan N, Mitsche M, et al.
J Am Chem Soc
. 2020 Mar;
142(13):6128-6138.
PMID: 32163279
TASIN (Truncated APC-Selective Inhibitors) compounds are selectively toxic to colorectal cancer cells with mutations, although their mechanism of action remains unknown. Here, we found that TASINs inhibit three enzymes in...
7.
Agarwal A, Tunison K, Mitsche M, McDonald J, Garg A
J Lipid Res
. 2019 Oct;
60(12):2057-2073.
PMID: 31653658
Loss of dysferlin (DYSF) protein in humans results in limb-girdle muscular dystrophy 2B, characterized by progressive loss of muscles in the distal limbs with impaired locomotion. The DYSF-null (Bla/J) mouse...
8.
Vale G, Martin S, Mitsche M, Thompson B, Eckert K, McDonald J
J Lipid Res
. 2019 Jan;
60(3):694-706.
PMID: 30610084
An unbiased sample preparation free of interferents (i.e., competing analytes, detergents, plastics) is critical to any lipid MS workflow. Here we present a novel three-phase lipid extraction (3PLE) technique using...
9.
Mitsche M, Hobbs H, Cohen J
J Biol Chem
. 2018 Mar;
293(18):6958-6968.
PMID: 29555681
Fatty liver disease (FLD) is a burgeoning health problem. A missense variant (I148M) in patatin-like phospholipase domain-containing protein 3 (PNPLA3) confers susceptibility to FLD, although the mechanism is not known....
10.
Zhang Y, Udayakumar D, Cai L, Hu Z, Kapur P, Kho E, et al.
JCI Insight
. 2017 Aug;
2(15).
PMID: 28768909
Background: Dysregulated lipid and glucose metabolism in clear cell renal cell carcinoma (ccRCC) has been implicated in disease progression, and whole tumor tissue-based assessment of these changes is challenged by...