Matei Bolborea
Overview
Explore the profile of Matei Bolborea including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
358
Followers
0
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Recent Articles
1.
Bolborea M
Methods Mol Biol
. 2025 Feb;
2882:305-316.
PMID: 39992516
Calcium imaging is a powerful tool to explore communication in neural networks. The hypothalamus is the region of the brain that regulates functions such as reproduction, appetite, lactation, stress, or...
2.
Guillot S, Lang C, Simonot M, Beckett D, Lule D, Balz L, et al.
Sci Transl Med
. 2025 Jan;
17(783):eadm7580.
PMID: 39879320
Sleep alterations have been described in several neurodegenerative diseases yet are currently poorly characterized in amyotrophic lateral sclerosis (ALS). This study investigates sleep macroarchitecture and related hypothalamic signaling disruptions in...
3.
Bolborea M, Vercruysse P, Daria T, Reiners J, Alami N, Guillot S, et al.
Acta Neuropathol
. 2023 Apr;
145(6):773-791.
PMID: 37058170
Amyotrophic lateral sclerosis (ALS) is associated with impaired energy metabolism, including weight loss and decreased appetite which are negatively correlated with survival. Neural mechanisms underlying metabolic impairment in ALS remain...
4.
Guillot S, Bolborea M, Dupuis L
Curr Opin Neurol
. 2021 Aug;
34(5):773-780.
PMID: 34343139
Purpose Of Review: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease targeting upper and lower motor neurons, inexorably leading to an early death. Defects in energy metabolism have been associated...
5.
Huang Q, Komarzynski S, Bolborea M, Finkenstadt B, Levi F
Front Physiol
. 2021 May;
12:659973.
PMID: 34040543
Background: Circadian rhythms in body temperature coordinate peripheral molecular clocks, hence they could potentially predict optimal treatment timing (chronotherapy) in individual patients. Circadian parameters in chest surface body temperature (Chesttemp)...
6.
Bolborea M, Langlet F
Am J Physiol Regul Integr Comp Physiol
. 2021 Apr;
320(6):R994-R1003.
PMID: 33826442
In vertebrates, the energy balance process is tightly controlled by complex neural circuits that sense metabolic signals and adjust food intake and energy expenditure in line with the physiological requirements...
7.
Levi F, Komarzynski S, Huang Q, Young T, Ang Y, Fuller C, et al.
Cancers (Basel)
. 2020 Jul;
12(7).
PMID: 32708950
The dichotomy index (I < O), a quantitative estimate of the circadian regulation of daytime activity and sleep, predicted overall cancer survival and emergency hospitalization, supporting its integration in a...
8.
Hypothalamic tanycytes generate acute hyperphagia through activation of the arcuate neuronal network
Bolborea M, Pollatzek E, Benford H, Sotelo-Hitschfeld T, Dale N
Proc Natl Acad Sci U S A
. 2020 Jun;
117(25):14473-14481.
PMID: 32513737
Hypothalamic tanycytes are chemosensitive glial cells that contact the cerebrospinal fluid in the third ventricle and send processes into the hypothalamic parenchyma. To test whether they can activate neurons of...
9.
Komarzynski S, Bolborea M, Huang Q, Finkenstadt B, Levi F
JCI Insight
. 2019 Aug;
4(18).
PMID: 31430260
BACKGROUNDCircadian timing of treatments can largely improve tolerability and efficacy in patients. Thus, drug metabolism and cell cycle are controlled by molecular clocks in each cell and coordinated by the...
10.
Benford H, Bolborea M, Pollatzek E, Lossow K, Hermans-Borgmeyer I, Liu B, et al.
Glia
. 2017 Feb;
65(5):773-789.
PMID: 28205335
Hypothalamic tanycytes are glial-like glucosensitive cells that contact the cerebrospinal fluid of the third ventricle, and send processes into the hypothalamic nuclei that control food intake and body weight. The...