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Martin Trapecar

Explore the profile of Martin Trapecar including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 522
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Recent Articles
11.
Yukl S, Khan S, Chen T, Trapecar M, Wu F, Xie G, et al.
J Virol . 2020 Oct; 95(2). PMID: 33115867
Latent HIV infection is the main barrier to cure, and most HIV-infected cells reside in the gut, where distinct but unknown mechanisms may promote viral latency. Transforming growth factor β...
12.
Trapecar M, Communal C, Velazquez J, Maass C, Huang Y, Schneider K, et al.
Cell Syst . 2020 Mar; 10(3):223-239.e9. PMID: 32191873
Although the association between the microbiome and IBD and liver diseases is known, the cause and effect remain elusive. By connecting human microphysiological systems of the gut, liver, and circulating...
13.
Marx U, Akabane T, Andersson T, Baker E, Beilmann M, Beken S, et al.
ALTEX . 2020 Mar; 37(3):365-394. PMID: 32113184
The first microfluidic microphysiological systems (MPS) entered the academic scene more than 15 years ago and were considered an enabling technology to human (patho)biology in vitro and, therefore, provide alternative...
14.
Khan S, Lew I, Wu F, Fritts L, Fontaine K, Tomar S, et al.
Nat Commun . 2019 Sep; 10(1):4344. PMID: 31554802
Innate immune responses to Zika virus (ZIKV) are dampened in the lower female reproductive tract (LFRT) compared to other tissues, but the mechanism that underlies this vulnerability is poorly understood....
15.
Hogan L, Vasquez J, Hobbs K, Hanhauser E, Aguilar-Rodriguez B, Hussien R, et al.
PLoS Pathog . 2018 Feb; 14(2):e1006856. PMID: 29470552
HIV-1-infected cells persist indefinitely despite the use of combination antiretroviral therapy (ART), and novel therapeutic strategies to target and purge residual infected cells in individuals on ART are urgently needed....
16.
Trapecar M, Khan S, Cohn B, Wu F, Sanjabi S
Mucosal Immunol . 2018 Feb; 11(4):1158-1167. PMID: 29456247
Determining the magnitude of local immune response during mucosal exposure to viral pathogens is critical to understanding the mechanism of viral pathogenesis. We previously showed that vaginal inoculation of lymphocytic...
17.
Khan S, Telwatte S, Trapecar M, Yukl S, Sanjabi S
AIDS Res Hum Retroviruses . 2017 Sep; 33(S1):S40-S58. PMID: 28882067
The single greatest challenge to an HIV cure is the persistence of latently infected cells containing inducible, replication-competent proviral genomes, which constitute only a small fraction of total or infected...
18.
Trapecar M, Khan S, Roan N, Chen T, Telwatte S, Deswal M, et al.
AIDS Res Hum Retroviruses . 2017 Sep; 33(S1):S31-S39. PMID: 28882052
The gastrointestinal (GI) tract harbors most of the body's immune cells and is also a major HIV reservoir in ART-treated patients. To achieve a cure, most HIV-infected cells must be...
19.
Trapecar M, Cencic A
Foods . 2017 Feb; 1(1):40-51. PMID: 28239090
The concept of functional and novel foods undoubtedly bears great potential as an asset to human health. However, this very same quest for ever new bioactive ingredients calls for reliable...
20.
Khan S, Woodruff E, Trapecar M, Fontaine K, Ezaki A, Borbet T, et al.
J Exp Med . 2016 Nov; 213(13):2913-2929. PMID: 27852793
Understanding the host immune response to vaginal exposure to RNA viruses is required to combat sexual transmission of this class of pathogens. In this study, using lymphocytic choriomeningitis virus (LCMV)...