Martin E Fernandez-Zapico
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Explore the profile of Martin E Fernandez-Zapico including associated specialties, affiliations and a list of published articles.
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173
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8659
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Recent Articles
1.
Jazieh K, Tsai J, Solomon S, Zhu M, Sinicrope F, Pedersen K, et al.
Clin Cancer Res
. 2025 Mar;
31(5):899-906.
PMID: 40025995
Purpose: KRAS G12C inhibitors can treat KRASG12C-mutant advanced colorectal cancers and pancreatic ductal adenocarcinomas (PDAC), but alterations in Kirsten rat sarcoma (KRAS), EGFR, BRAF, MAP2K1, and other genes bypass KRAS...
2.
Tesfay M, Zhang Y, Ferdous K, Taylor M, Cios A, Shelton R, et al.
Mol Ther Oncol
. 2025 Jan;
32(4):200913.
PMID: 39758249
Members of the genus including Jurona virus (JURV) have emerged as promising immunotherapeutic agents, characterized by their tumor selectivity, fast kinetics, low seroprevalence, and minimal toxicity in humans. Here, we...
3.
Kwon J, Vera R, Fernandez-Zapico M
Cell Signal
. 2025 Jan;
127:111584.
PMID: 39756502
The tumor microenvironment (TME) has been linked with the pathogenesis of pancreatic ductal adenocarcinoma (PDAC), the most common histological subtype of pancreatic cancer. A central component of the TME are...
4.
Garay M, Mazo T, Ferrero V, Barotto N, Lagares C, Granton M, et al.
Carcinogenesis
. 2025 Jan;
46(1).
PMID: 39742417
Pancreatic cancer is a devastating malignancy in great need of new and more effective treatment approaches. In recent years, studies have indicated that nutritional interventions, particularly nutraceuticals, may provide novel...
5.
Dalvin L, Andrews-Pfannkoch C, Miley D, Hogenson T, Erickson S, Malpotra S, et al.
Invest Ophthalmol Vis Sci
. 2024 Nov;
65(13):60.
PMID: 39601636
Purpose: A lack of representative human disease models has limited the translation of new and more effective treatments in uveal melanoma (UM), the most common primary adult intraocular malignancy. To...
6.
Vera R, Lamberti M, Gonzalez A, Fernandez-Zapico M
Pancreatology
. 2024 Aug;
24(6):878-886.
PMID: 39095296
Dysregulation of the epigenomic landscape of tumor cells has been implicated in the pathogenesis of pancreatic cancer. However, these alterations are not only restricted to neoplastic cells. The behavior of...
7.
Giammona A, De Vellis C, Crivaro E, Maresca L, Amoriello R, Ricci F, et al.
J Exp Clin Cancer Res
. 2024 Aug;
43(1):214.
PMID: 39090759
Background: Melanoma progression is based on a close interaction between cancer cells and immune cells in the tumor microenvironment (TME). Thus, a better understanding of the mechanisms controlling TME dynamics...
8.
LaRue-Nolan K, Raja Arul G, Sigafoos A, Shi J, Fernandez-Zapico M
Biochem J
. 2024 Jul;
481(15):983-997.
PMID: 39078225
Pancreatic cancer is a malignancy arising from the endocrine or exocrine compartment of this organ. Tumors from exocrine origin comprise over 90% of all pancreatic cancers diagnosed. Of these, pancreatic...
9.
Sigafoos A, Tolosa E, Carr R, Fernandez-Barrena M, Almada L, Pease D, et al.
Cancer Res Commun
. 2024 Jun;
4(7):1677-1689.
PMID: 38896052
Aberrant activation of GLI transcription factors has been implicated in the pathogenesis of different tumor types including pancreatic ductal adenocarcinoma. However, the mechanistic link with established drivers of this disease...
10.
Zhang T, Chen S, Li L, Jin Y, Liu S, Liu Z, et al.
JCI Insight
. 2024 May;
9(13).
PMID: 38781030
Acute pancreatitis (AP) is among the most common hospital gastrointestinal diagnoses; understanding the mechanisms underlying the severity of AP is critical for development of new treatment options for this disease....