Martin Balouch
Overview
Explore the profile of Martin Balouch including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
32
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Recent Articles
1.
Meta-Analysis of Permeability Literature Data Shows Possibilities and Limitations of Popular Methods
Storchmannova K, Balouch M, Juracka J, Stepanek F, Berka K
Mol Pharm
. 2025 Feb;
22(3):1293-1304.
PMID: 39977255
Permeability is an important molecular property in drug discovery, as it co-determines pharmacokinetics whenever a drug crosses the phospholipid bilayer, e.g., into the cell, in the gastrointestinal tract, or across...
2.
Simonova A, Balouch M, Stepanek F, Krizek T
Anal Bioanal Chem
. 2025 Feb;
PMID: 39939418
This study explores the potential of using liposomal electrokinetic chromatography as a ranking method for the rapid and simultaneous evaluation of drug-membrane interactions of a larger group of substances and...
3.
Kurfirt M, cervenkova Stastna L, Dracinsky M, Pohl R, Cisarova I, Sykora J, et al.
J Org Chem
. 2024 Aug;
89(17):11875-11890.
PMID: 39178339
-Acetyllactosamine is a common saccharide motif found in various biologically active glycans. This motif usually works as a backbone for additional modifications and thus significantly influences glycan conformational behavior and...
4.
Odehnalova K, Balouch M, Storchmannova K, Petrova E, Konefal M, Zadrazil A, et al.
Mol Pharm
. 2024 Apr;
21(6):2673-2683.
PMID: 38682796
The permeation of small molecules across biological membranes is a crucial process that lies at the heart of life. Permeation is involved not only in the maintenance of homeostasis at...
5.
Petrova E, Chvila S, Balouch M, Stepanek F, Zbytovska J
Int J Pharm
. 2023 Nov;
648:123577.
PMID: 37931726
Imiquimod (IMQ) is an immunostimulating agent used in the treatment of basal cell carcinoma and actinic keratosis. Due to its low solubility and poor skin bioavailability, the dermal formulation of...
6.
Balouch M, Storchmannova K, Stepanek F, Berka K
Mol Pharm
. 2023 Mar;
20(4):2119-2127.
PMID: 36939094
Encapsulation into liposomes is a formulation strategy that can improve efficacy and reduce side effects of active pharmaceutical ingredients (APIs) that exhibit poor biodistribution or pharmacokinetics when administered alone. However,...
7.
Lizonova D, Frei S, Balouch M, Zadrazil A, Stepanek F
ACS Appl Bio Mater
. 2022 Jan;
4(6):4833-4840.
PMID: 35007032
Lipid bilayers are the basic structural components of all living systems, forming the membranes of cells, sub-cellular organelles, and extracellular vesicles. A class of man-made lipidic vesicles called multilobed magnetic...
8.
Salamunova P, Salon I, Ruphuy G, Kroupova J, Balouch M, Hanus J, et al.
Eur J Pharm Biopharm
. 2021 Aug;
168:15-25.
PMID: 34411641
Yeast glucan particles are porous polysaccharide cell walls extracted from Saccharomyces cerevisiae. Being mildly immunogenic, they are efficiently phagocytosed and have therefore been proposed as possible vehicles for drug delivery....
9.
Soltys M, Zuza D, Boleslavska T, Machac Akhlasova S, Balouch M, Kovacik P, et al.
Int J Pharm
. 2021 Aug;
607:120982.
PMID: 34371148
The sorption of poorly aqueous soluble active pharmaceutical ingredients (API) to mesoporous silica carriers is an increasingly common formulation strategy for dissolution rate enhancement for this challenging group of substances....
10.
Hamala V, cervenkova Stastna L, Kurfirt M, Curinova P, Balouch M, Hrstka R, et al.
Org Biomol Chem
. 2021 May;
19(20):4497-4506.
PMID: 33949602
Fully acetylated deoxyfluorinated hexosamine analogues and non-fluorinated 3,4,6-tri-O-acylated N-acetyl-hexosamine hemiacetals have previously been shown to display moderate anti-proliferative activity. We prepared a set of deoxyfluorinated GlcNAc and GalNAc hemiacetals that...