Lucie cervenkova Stastna
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Explore the profile of Lucie cervenkova Stastna including associated specialties, affiliations and a list of published articles.
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16
Citations
43
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Recent Articles
1.
Mullerova M, Tarach P, Strasak T, Curinova P, Petrickovic R, Zavodna T, et al.
ACS Omega
. 2025 Jan;
10(1):1047-1060.
PMID: 39829590
Efficient and safe carriers of genetic material are crucial for advancing gene therapy. Three new series of cationic dendritic nanocarriers based on a carbosilane scaffold, differentiated by peripheral modifications: saccharide...
2.
Kurfirt M, cervenkova Stastna L, Dracinsky M, Pohl R, Cisarova I, Sykora J, et al.
J Org Chem
. 2024 Aug;
89(17):11875-11890.
PMID: 39178339
-Acetyllactosamine is a common saccharide motif found in various biologically active glycans. This motif usually works as a backbone for additional modifications and thus significantly influences glycan conformational behavior and...
3.
Kurfirt M, Hamala V, Beranek J, cervenkova Stastna L, cerveny J, Dracinsky M, et al.
Bioorg Chem
. 2024 May;
147:107395.
PMID: 38705105
Fluorination of carbohydrate ligands of lectins is a useful approach to examine their binding profile, improve their metabolic stability and lipophilicity, and convert them into F NMR-active probes. However, monofluorination...
4.
Chaloupecka E, Kurfirt M, cervenkova Stastna L, Karban J, Dracinsky M
Bioorg Chem
. 2024 Apr;
147:107388.
PMID: 38678775
In this study, we investigated the potential of long-range fluorine-carbon J-coupling for determining the structures of deoxyfluorinated disaccharides. Three disaccharides, previously synthesized as potential galectin inhibitors, exhibited through-space fluorine-carbon J-couplings....
5.
Edr A, Wrobel D, Krupkova A, cervenkova Stastna L, Curinova P, Novak A, et al.
Int J Mol Sci
. 2022 Feb;
23(4).
PMID: 35216229
Supramolecular structures, such as micelles, liposomes, polymerosomes or dendrimerosomes, are widely studied and used as drug delivery systems. The behavior of amphiphilic building blocks strongly depends on their spatial distribution...
6.
Salvadori K, Krupkova A, cervenkova Stastna L, Mullerova M, Eigner V, Strasak T, et al.
Molecules
. 2021 Sep;
26(18).
PMID: 34577148
The repetition of urea-based binding units within the receptor structure does not only lead to monomer properties multiplication. As confirmed by spectroscopic studies, UV-Vis and H-NMR in classical or competitive...
7.
Kurfirt M, Dracinsky M, cervenkova Stastna L, Curinova P, Hamala V, Hovorkova M, et al.
Chemistry
. 2021 Jul;
27(51):13040-13051.
PMID: 34216419
Galectins are widely expressed galactose-binding lectins implied, for example, in immune regulation, metastatic spreading, and pathogen recognition. N-Acetyllactosamine (Galβ1-4GlcNAc, LacNAc) and its oligomeric or glycosylated forms are natural ligands of...
8.
Curinova P, Winkler M, Krupkova A, Cisarova I, Budka J, Wun C, et al.
ACS Omega
. 2021 Jun;
6(23):15514-15522.
PMID: 34151129
A novel approach to inducing anion transport over the dialytic membrane was proposed and successfully tested using the dihydrogen phosphate anion. The anion receptor based on isophthalamide was anchored on...
9.
Hamala V, cervenkova Stastna L, Kurfirt M, Curinova P, Dracinsky M, Karban J
Beilstein J Org Chem
. 2021 Jun;
17:1086-1095.
PMID: 34093878
Multiple fluorination of glycostructures has emerged as an attractive way of modulating their protein affinity, metabolic stability, and lipophilicity. Here we described the synthesis of a series of mono-, di-...
10.
Hamala V, cervenkova Stastna L, Kurfirt M, Curinova P, Balouch M, Hrstka R, et al.
Org Biomol Chem
. 2021 May;
19(20):4497-4506.
PMID: 33949602
Fully acetylated deoxyfluorinated hexosamine analogues and non-fluorinated 3,4,6-tri-O-acylated N-acetyl-hexosamine hemiacetals have previously been shown to display moderate anti-proliferative activity. We prepared a set of deoxyfluorinated GlcNAc and GalNAc hemiacetals that...