Marko Z Vatamaniuk
Overview
Explore the profile of Marko Z Vatamaniuk including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
694
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wang H, Vatamaniuk M, Zhao Z, Lei X
Antioxidants (Basel)
. 2023 Apr;
12(4).
PMID: 37107224
Our laboratory previously revealed that regenerating islets-derived protein 2 (REG2) was diminished in pancreatic islets of glutathione peroxidase-1-overexpressing mice (). It remained unknown if there is an inverse relationship between...
2.
Vatamaniuk M, Huang R, Zhao Z, Lei X
Antioxidants (Basel)
. 2023 Apr;
12(4).
PMID: 37107221
Transition metals such as iron, copper and zinc are required for the normal functioning of biological tissues, whereas others, such as cadmium, are potentially highly toxic. Any disturbances in homeostasis...
3.
Yan X, Zhao Z, Weaver J, Sun T, Yun J, Roneker C, et al.
Redox Biol
. 2022 Sep;
56:102457.
PMID: 36063729
We previously reported a depletion of murine regenerating islet-derived protein 2 (REG2) in pancreatic islets of glutathione peroxidase-1 (Gpx1) overexpressing (OE) mice. The present study was to explore if and...
4.
Lei X, Combs Jr G, Sunde R, Caton J, Arthington J, Vatamaniuk M
Annu Rev Nutr
. 2022 Jun;
42:337-375.
PMID: 35679623
This review traces the discoveries that led to the recognition of selenium (Se) as an essential nutrient and discusses Se-responsive diseases in animals and humans in the context of current...
5.
Yun J, Zhao Z, Yan X, Vatamaniuk M, Lei X
Free Radic Biol Med
. 2019 Feb;
134:385-393.
PMID: 30703484
Our group previously demonstrated that overexpression of selenium-dependent glutathione peroxidase-1 (GPX1) in mice (OE) led to escalated glucose-stimulated insulin secretion and hyperinsulinemia. Because we found a strong correlation of this...
6.
Yan X, Pepper M, Vatamaniuk M, Roneker C, Li L, Lei X
J Nutr
. 2012 Sep;
142(11):1975-82.
PMID: 23014491
This study was conducted to determine whether dietary Se deficiency precluded overproduction of glutathione peroxidase-1 (GPX1) activity in mice overexpressing (OE) this gene and thus rescued their type 2 diabetes-like...
7.
Lei X, Vatamaniuk M
Antioxid Redox Signal
. 2010 Jul;
14(3):489-503.
PMID: 20618069
Pancreatic islets contain low activities of catalase, selenium-dependent glutathione peroxidase 1 (GPX1), and Cu,Zn-superoxide dismutase 1 (SOD1). Thus, enhancing expression of these enzymes in islets has been unquestionably favored. However,...
8.
Knockouts of SOD1 and GPX1 exert different impacts on murine islet function and pancreatic integrity
Wang X, Vatamaniuk M, Roneker C, Pepper M, Hu L, Simmons R, et al.
Antioxid Redox Signal
. 2010 Jul;
14(3):391-401.
PMID: 20586612
Metabolic subtlety and clinical relevance of different forms of reactive oxygen species in diabetes remain unclear. Using single knockout of Cu,Zn-superoxide dismutase (SOD1(-/-)) or Se-glutathione peroxidase-1 (GPX1(-/-)) and their double-knockout...
9.
Pepper M, Vatamaniuk M, Yan X, Roneker C, Lei X
Antioxid Redox Signal
. 2010 Jun;
14(3):383-90.
PMID: 20578960
We previously reported a spontaneous development of type 2 diabetes-like phenotypes in glutathione peroxidase-1 (GPX1)-overexpressing (OE) mice. Diet restriction of these mice rescued all their phenotypes, except for hyperinsulinemia and...
10.
Gao N, LeLay J, Vatamaniuk M, Rieck S, Friedman J, Kaestner K
Genes Dev
. 2009 Jan;
22(24):3435-48.
PMID: 19141476
The onset of pancreas development in the foregut endoderm is marked by activation of the homeobox gene Pdx1 (IPF1). Pdx1 is essential for the expansion of the pancreatic primordium and...