Franz M Matschinsky
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Explore the profile of Franz M Matschinsky including associated specialties, affiliations and a list of published articles.
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84
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3299
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Recent Articles
1.
Genetic activation of glucokinase in a minority of pancreatic beta cells causes hypoglycemia in mice
Chen K, Doliba N, May C, Roman J, Ustione A, Tembo T, et al.
Life Sci
. 2022 Sep;
309:120952.
PMID: 36100080
Aims: Glucokinase (GK) is expressed in the glucose-sensing cells of the islets of Langerhans and plays a critical role in glucose homeostasis. Here, we tested the hypothesis that genetic activation...
2.
Doliba N, Rozo A, Roman J, Qin W, Traum D, Gao L, et al.
J Clin Invest
. 2022 Jun;
132(11).
PMID: 35642629
BACKGROUNDMultiple islet autoantibodies (AAbs) predict the development of type 1 diabetes (T1D) and hyperglycemia within 10 years. By contrast, T1D develops in only approximately 15% of individuals who are positive...
3.
Wilson D, Matschinsky F
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628359
Maintaining a robust, stable source of energy for doing chemical and physical work is essential to all living organisms. In eukaryotes, metabolic energy (ATP) production and consumption occurs in two...
4.
Wilson D, Matschinsky F
Front Physiol
. 2021 May;
12:658997.
PMID: 33967829
Living organisms require continuous input of energy for their existence. As a result, life as we know it is based on metabolic processes that extract energy from the environment and...
5.
Wilson D, Matschinsky F
Front Physiol
. 2020 Nov;
11:584891.
PMID: 33178048
Nutrient delivery to the brain presents a unique challenge because the tissue functions as a computer system with in the order of 200,000 neurons/mm. Penetrating arterioles bud from surface arteries...
6.
Wilson D, Matschinsky F
Med Hypotheses
. 2020 Mar;
140:109638.
PMID: 32113062
Throughout the world, ethanol is both an important commercial commodity and a source of major medical and social problems. Ethanol readily passes through biological membranes and distributes throughout the body....
7.
Wilson D, Matschinsky F
Med Hypotheses
. 2019 Aug;
132:109375.
PMID: 31454640
Hyperbaric oxygen exposure is a recent hazzard for higher animals that originated as humans began underwater construction, exploration, and sports. Exposure can lead to abnormal brain EEG, convulsions, and death,...
8.
Zhu L, Rossi M, Cohen A, Pham J, Zheng H, Dattaroy D, et al.
Proc Natl Acad Sci U S A
. 2019 Aug;
116(37):18684-18690.
PMID: 31451647
Given the global epidemic in type 2 diabetes, novel antidiabetic drugs with increased efficacy and reduced side effects are urgently needed. Previous work has shown that M muscarinic acetylcholine (ACh)...
9.
Zhu L, Dattaroy D, Pham J, Wang L, Barella L, Cui Y, et al.
JCI Insight
. 2019 Apr;
5.
PMID: 31012868
Glucagon, a hormone released from pancreatic alpha-cells, plays a key role in maintaining proper glucose homeostasis and has been implicated in the pathophysiology of diabetes. In vitro studies suggest that...
10.
Wilson D, Matschinsky F
J Appl Physiol (1985)
. 2019 Apr;
126(4):1172.
PMID: 30998441
No abstract available.