Mark L Kahn
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Explore the profile of Mark L Kahn including associated specialties, affiliations and a list of published articles.
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121
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4123
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Recent Articles
11.
Gao S, Tang A, Wang M, Buchholz D, Imbiakha B, Yang J, et al.
bioRxiv
. 2023 Aug;
PMID: 37546961
Endothelial damage and vascular pathology have been recognized as major features of COVID-19 since the beginning of the pandemic. Two main theories regarding how Severe Acute Respiratory Syndrome Coronavirus 2...
12.
Jannaway M, Iyer D, Mastrogiacomo D, Li K, Sung D, Yang Y, et al.
Cell Rep
. 2023 Jul;
42(7):112777.
PMID: 37454290
Lymphatic capillaries develop discontinuous cell-cell junctions that permit the absorption of large macromolecules, chylomicrons, and fluid from the interstitium. While excessive vascular endothelial growth factor 2 (VEGFR2) signaling can remodel...
13.
Hoofnagle M, Hess A, Nalugo M, Ghosh S, Hughes S, Fuchs A, et al.
J Trauma Acute Care Surg
. 2023 Apr;
95(2):197-204.
PMID: 37072887
Objectives: Deep venous thrombosis (DVT) causes significant morbidity and mortality after trauma. Recently, we have shown that blood flow patterns at vein valves induce oscillatory stress genes, which maintain an...
14.
Sung D, Chen M, Dominguez M, Mahadevan A, Chen X, Yang J, et al.
Nat Cardiovasc Res
. 2023 Mar;
1(11):1006-1021.
PMID: 36910472
Sinusoids are specialized, low pressure blood vessels in the liver, bone marrow, and spleen required for definitive hematopoiesis. Unlike other blood endothelial cells (ECs), sinusoidal ECs express high levels of...
15.
Srinath A, Xie B, Li Y, Sone J, Romanos S, Chen C, et al.
Commun Med (Lond)
. 2023 Mar;
3(1):35.
PMID: 36869161
Background: Cavernous angiomas (CAs) affect 0.5% of the population, predisposing to serious neurologic sequelae from brain bleeding. A leaky gut epithelium associated with a permissive gut microbiome, was identified in...
16.
Tang A, Buchholz D, Szigety K, Imbiakha B, Gao S, Frankfurter M, et al.
PLoS Biol
. 2023 Feb;
21(2):e3001989.
PMID: 36745682
Angiotensin-converting enzyme 2 (ACE2) is the cell-surface receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While its central role in Coronavirus Disease 2019 (COVID-19) pathogenesis is indisputable, there remains...
17.
Chen X, Tang A, Tober J, Yang J, Leu N, Sterling S, et al.
Dev Cell
. 2022 Dec;
57(23):2652-2660.e3.
PMID: 36473461
Placental fetal macrophages (fMacs) are the only immune cells on the fetal side of the placental barrier. Mouse models have not been used to test their function because they have...
18.
Johnson N, Na J, Monaghan K, Tang A, Tian Y, Leu N, et al.
Cell Mol Gastroenterol Hepatol
. 2022 Aug;
14(6):1334-1337.e1.
PMID: 36031151
No abstract available.
19.
Hall J, Farzaneh S, Babakhani Galangashi R, Pujari A, Sweet D, Kahn M, et al.
J R Soc Interface
. 2022 Aug;
19(193):20220223.
PMID: 36000230
Lymphatic vessel contractions generate net antegrade pulsatile lymph flow. By contrast, impaired lymphatic vessels are often associated with lymphoedema and altered lymph flow. The effect of lymphoedema on the lymph...
20.
Romanos S, Srinath A, Li Y, Xie B, Chen C, Li Y, et al.
Transl Stroke Res
. 2022 Jun;
14(4):513-529.
PMID: 35715588
Patients with familial cerebral cavernous malformation (CCM) inherit germline loss of function mutations and are susceptible to progressive development of brain lesions and neurological sequelae during their lifetime. To date,...