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Mark Jeeves

Explore the profile of Mark Jeeves including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 706
Followers 0
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Recent Articles
1.
Ferrante L, Rajpoot K, Jeeves M, Ludwig C
Wellcome Open Res . 2023 May; 7:262. PMID: 37008249
Metabolism is essential for cell survival and proliferation. A deep understanding of the metabolic network and its regulatory processes is often vital to understand and overcome disease. Stable isotope tracing...
2.
Willcox C, Salim M, Begley C, Karunakaran M, Easton E, von Klopotek C, et al.
Cell Rep . 2023 Mar; 42(4):112321. PMID: 36995939
Vγ9Vδ2 T cells play critical roles in microbial immunity by detecting target cells exposed to pathogen-derived phosphoantigens (P-Ags). Target cell expression of BTN3A1, the "P-Ag sensor," and BTN2A1, a direct...
3.
Vilaplana-Lopera N, Cuminetti V, Almaghrabi R, Papatzikas G, Rout A, Jeeves M, et al.
Elife . 2022 Sep; 11. PMID: 36052997
Acute myeloid leukaemia (AML) cells interact and modulate components of their surrounding microenvironment into their own benefit. Stromal cells have been shown to support AML survival and progression through various...
4.
Hall S, Clifton L, Sridhar P, Hardy D, Wotherspoon P, Wright J, et al.
Biophys J . 2021 Nov; 120(23):5295-5308. PMID: 34757080
The outer membrane of Gram-negative bacteria presents a robust physicochemical barrier protecting the cell from both the natural environment and acting as the first line of defense against antimicrobial materials....
5.
Bryant J, Morris F, Knowles T, Maderbocus R, Heinz E, Boelter G, et al.
Elife . 2020 Dec; 9. PMID: 33315009
The Gram-negative outer-membrane envelops the bacterium and functions as a permeability barrier against antibiotics, detergents, and environmental stresses. Some virulence factors serve to maintain the integrity of the outer membrane,...
6.
Jeeves M, Roberts J, Ludwig C
Magn Reson Chem . 2020 Aug; 59(3):287-299. PMID: 32830359
Nuclear magnetic resonance (NMR) spectroscopy is integral to metabolic studies; yet, it can suffer from the long acquisition times required to collect data of sufficient signal strength and resolution. The...
7.
Tong M, Jeeves M, Rajesh S, Ludwig C, Lenoir M, Kumar J, et al.
Biomol NMR Assign . 2020 Jun; 14(2):221-225. PMID: 32535836
The CaMK subfamily of Ser/Thr kinases are regulated by calmodulin interactions with their C-terminal regions. They are exemplified by Ca/calmodulin dependent protein kinase 1δ which is known as CaMK1D, CaMKIδ...
8.
Milton-Harris L, Jeeves M, Walker S, Ward S, Mancini E
Oncotarget . 2020 Jun; 11(19):1737-1748. PMID: 32477463
Ectopic expression in T-cell precursors of LIM only protein 2 (LMO2), a key factor in hematopoietic development, has been linked to the onset of T-cell acute lymphoblastic leukaemia (T-ALL). In...
9.
Cranford-Smith T, Jamshad M, Jeeves M, Chandler R, Yule J, Robinson A, et al.
J Biol Chem . 2020 Apr; 295(21):7516-7528. PMID: 32241912
The ATPase SecA is an essential component of the bacterial Sec machinery, which transports proteins across the cytoplasmic membrane. Most SecA proteins contain a long C-terminal tail (CTT). In ,...
10.
Karunakaran M, Willcox C, Salim M, Paletta D, Fichtner A, Noll A, et al.
Immunity . 2020 Mar; 52(3):487-498.e6. PMID: 32155411
Vγ9Vδ2 T cells respond in a TCR-dependent fashion to both microbial and host-derived pyrophosphate compounds (phosphoantigens, or P-Ag). Butyrophilin-3A1 (BTN3A1), a protein structurally related to the B7 family of costimulatory...