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Christian Ludwig

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Articles 126
Citations 1648
Followers 0
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Recent Articles
1.
Ludwig C
Metabolites . 2025 Jan; 15(1). PMID: 39852390
NMR spectroscopy is a powerful technique for studying metabolism, either in metabolomics settings or through tracing with stable isotope-enriched metabolic precursors. MetaboLabPy (version 0.9.66) is a free and open-source software...
2.
Patel K, Nath J, Smith T, Darius T, Thakker A, Dimeloe S, et al.
Transplant Direct . 2024 Dec; 11(1):e1736. PMID: 39668892
Background: The provision of a metabolic substrate is one mechanism by which hypothermic machine perfusion (HMP) of kidneys provides clinical benefit. This study aimed to describe metabolism in ex vivo...
3.
Mendes L, Gama-Almeida M, Reis D, Silva A, Neris R, Galliez R, et al.
Viruses . 2024 Nov; 16(11). PMID: 39599883
COVID-19 can range from a mild to severe acute respiratory syndrome and also could result in multisystemic damage. Additionally, many people develop post-acute symptoms associated with immune and metabolic disturbances...
4.
Ta L, Corrigan S, Tselepis C, Iqbal T, Ludwig C, Horniblow R
J Control Release . 2024 Sep; 375:495-512. PMID: 39284524
The process of microencapsulation and the development of microparticle-based drug formulations have gained increased pharmaceutical interest, particularly for drug delivery and bacterial-encapsulation purposes for probiotic delivery. Existing studies have examined...
5.
Atkins J, Keevil B, Taylor A, Ludwig C, Hawley J
Clin Chem Lab Med . 2024 Aug; 63(1):154-163. PMID: 39097844
Objectives: 7α-Hydroxy-4-cholesten-3-one (C4) is the common intermediary of both primary bile acids. C4 is recommended by the British Society of Gastroenterology for the investigation of bile acid diarrhoea (BAD) in...
6.
Cen T, Zhang Z, Torrent L, Muller E, Ludwig C, Testino A
Sci Rep . 2024 Jul; 14(1):17312. PMID: 39068190
Metal azides are highly energetic materials that release a large amount of gas upon detonation. They also release metal particles, generating an aerosol. The most common azide is sodium azide...
7.
Sostare E, Bowen T, Lawson T, Freier A, Li X, Lloyd G, et al.
Chem Res Toxicol . 2024 Jun; 37(6):923-934. PMID: 38842447
Benchmark dose (BMD) modeling estimates the dose of a chemical that causes a perturbation from baseline. Transcriptional BMDs have been shown to be relatively consistent with apical end point BMDs,...
8.
Stanulovic V, Al Omair S, Reed M, Roberts J, Potluri S, Fulton-Ward T, et al.
Haematologica . 2024 May; 109(11):3505-3519. PMID: 38813748
T-cell acute lymphoblastic leukemia (T-ALL) is a cancer of the immune system. Approximately 20% of pediatric and 50% of adult T-ALL patients have refractory disease or relapse and die from...
9.
Cuozzo F, Viloria K, Shilleh A, Nasteska D, Frazer-Morris C, Tong J, et al.
Cell Rep . 2024 Apr; 43(4):114047. PMID: 38607916
Using C glucose labeling coupled to gas chromatography-mass spectrometry and 2D H-C heteronuclear single quantum coherence NMR spectroscopy, we have obtained a comparative high-resolution map of glucose fate underpinning β...
10.
Szatkowska R, Furmanek E, Kierzek A, Ludwig C, Adamczyk M
Int J Mol Sci . 2023 Oct; 24(19). PMID: 37834211
RNA polymerase III (RNAP III) holoenzyme activity and the processing of its products have been linked to several metabolic dysfunctions in lower and higher eukaryotes. Alterations in the activity of...