Caezar Al-Jassar
Overview
Explore the profile of Caezar Al-Jassar including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
132
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Recent Articles
1.
Odintsova E, Mohammed F, Trieber C, Rodriguez-Zamora P, Al-Jassar C, Huang T, et al.
Commun Biol
. 2020 Feb;
3(1):83.
PMID: 32081916
Plakin proteins form connections that link the cell membrane to the intermediate filament cytoskeleton. Their interactions are mediated by a highly conserved linker domain through an unresolved mechanism. Here analysis...
2.
Joseph N, Al-Jassar C, Johnson C, Andreeva A, Barnabas D, Freund S, et al.
Cell Rep
. 2018 May;
23(9):2805-2818.
PMID: 29847808
Ciliopathies are a group of genetic disorders caused by a failure to form functional cilia. Due to a lack of structural information, it is currently poorly understood how ciliopathic mutations...
3.
Willhoft O, Kerr R, Patel D, Zhang W, Al-Jassar C, Daviter T, et al.
Sci Rep
. 2017 Feb;
7:41626.
PMID: 28139700
The essential cochaperone Sgt1 recruits Hsp90 chaperone activity to a range of cellular factors including SCF E3 ubiquitin ligases and the kinetochore in eukaryotes. In these pathways Sgt1 interacts with...
4.
Al-Jassar C, Andreeva A, Barnabas D, McLaughlin S, Johnson C, Yu M, et al.
Structure
. 2016 Dec;
25(1):146-156.
PMID: 28017521
Cilia are thin cell projections with essential roles in cell motility, fluid movement, sensing, and signaling. They are templated from centrioles that dock against the plasma membrane and subsequently extend...
5.
Fogl C, Mohammed F, Al-Jassar C, Jeeves M, Knowles T, Rodriguez-Zamora P, et al.
Nat Commun
. 2016 Mar;
7:10827.
PMID: 26935805
Plakin proteins form critical connections between cell junctions and the cytoskeleton; their disruption within epithelial and cardiac muscle cells cause skin-blistering diseases and cardiomyopathies. Envoplakin has a single plakin repeat...
6.
Jeeves M, Fogl C, Al-Jassar C, Chidgey M, Overduin M
Biomol NMR Assign
. 2015 Nov;
10(1):167-70.
PMID: 26590577
The plakin repeat domain is a distinctive hallmark of the plakin superfamily of proteins, which are found within all epithelial tissues. Plakin repeat domains mediate the interactions of these proteins...
7.
Al-Jassar C, Bernado P, Chidgey M, Overduin M
PLoS One
. 2013 Aug;
8(7):e69767.
PMID: 23922795
Envoplakin, periplakin and desmoplakin are cytoskeletal proteins that provide structural integrity within the skin and heart by resisting shear forces. Here we reveal the nature of unique hinges within their...
8.
Al-Jassar C, Bikker H, Overduin M, Chidgey M
J Mol Biol
. 2013 Aug;
425(21):4006-22.
PMID: 23911551
Desmosomes are dynamic junctions between cells that maintain the structural integrity of skin and heart tissues by withstanding shear forces. Mutations in component genes cause life-threatening conditions including arrhythmogenic right...
9.
Al-Jassar C, Knowles T, Jeeves M, Kami K, Behr E, Bikker H, et al.
J Mol Biol
. 2011 Jul;
411(5):1049-61.
PMID: 21756917
Desmoplakin is a cytoplasmic desmosomal protein that plays a vital role in normal intercellular adhesion. Mutations in desmoplakin can result in devastating skin blistering diseases and arrhythmogenic right ventricular cardiomyopathy,...