Marieke L Kuijjer
Overview
Explore the profile of Marieke L Kuijjer including associated specialties, affiliations and a list of published articles.
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47
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1714
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Recent Articles
1.
Ferenc K, Rauluseviciute I, Hovan L, Kumar V, Kuijjer M, Mathelier A
Bioinformatics
. 2024 Oct;
40(11).
PMID: 39436982
Summary: Since high-throughput techniques became a staple in biological science laboratories, computational algorithms, and scientific software have boomed. However, the development of bioinformatics software usually lacks software development quality standards....
2.
Meijer D, Ruano D, Briaire-de Bruijn I, Wijers-Koster P, van de Sande M, Gelderblom H, et al.
Genes Chromosomes Cancer
. 2024 Jul;
63(7):e23253.
PMID: 39023390
Osteosarcoma is a primary bone tumor that exhibits a complex genomic landscape characterized by gross chromosomal abnormalities. Osteosarcoma patients often develop metastatic disease, resulting in limited therapeutic options and poor...
3.
Green D, Ewijk R, Tirtei E, Andreou D, Baecklund F, Baumhoer D, et al.
Clin Cancer Res
. 2024 Jun;
30(16):3395-3406.
PMID: 38869831
Osteosarcoma and Ewing sarcoma are bone tumors mostly diagnosed in children, adolescents, and young adults. Despite multimodal therapy, morbidity is high and survival rates remain low, especially in the metastatic...
4.
Osorio D, Capasso A, Eckhardt S, Giri U, Somma A, Pitts T, et al.
Nat Comput Sci
. 2024 Mar;
4(3):237-250.
PMID: 38438786
Single-cell technologies enable high-resolution studies of phenotype-defining molecular mechanisms. However, data sparsity and cellular heterogeneity make modeling biological variability across single-cell samples difficult. Here we present SCORPION, a tool that...
5.
De Marzio M, Glass K, Kuijjer M
BMC Biol
. 2023 Dec;
21(1):296.
PMID: 38155351
No abstract available.
6.
Struck E, Belova T, Hsieh P, Odeberg J, Kuijjer M, Dusart P, et al.
J Immunol
. 2023 Nov;
212(1):117-129.
PMID: 38019121
The vascular endothelium acts as a dynamic interface between blood and tissue. TNF-α, a major regulator of inflammation, induces endothelial cell (EC) transcriptional changes, the overall response dynamics of which...
7.
Belova T, Biondi N, Hsieh P, Lutsik P, Chudasama P, Kuijjer M
NAR Cancer
. 2023 Jul;
5(3):zcad037.
PMID: 37492373
Characterizing inter-tumor heterogeneity is crucial for selecting suitable cancer therapy, as the presence of diverse molecular subgroups of patients can be associated with disease outcome or response to treatment. While...
8.
Pavlovic M, Scheffer L, Motwani K, Kanduri C, Kompova R, Vazov N, et al.
Nat Mach Intell
. 2023 Jul;
3(11):936-944.
PMID: 37396030
Adaptive immune receptor repertoires (AIRR) are key targets for biomedical research as they record past and ongoing adaptive immune responses. The capacity of machine learning (ML) to identify complex discriminative...
9.
Ben Guebila M, Wang T, Lopes-Ramos C, Fanfani V, Weighill D, Burkholz R, et al.
Genome Biol
. 2023 Mar;
24(1):45.
PMID: 36894939
Inference and analysis of gene regulatory networks (GRNs) require software that integrates multi-omic data from various sources. The Network Zoo (netZoo; netzoo.github.io) is a collection of open-source methods to infer...
10.
Birkealv S, Harland M, Matsuyama L, Rashid M, Mehta I, Laye J, et al.
J Pathol
. 2022 Oct;
259(1):56-68.
PMID: 36219477
Melanoma is a heterogenous malignancy with an unpredictable clinical course. Most patients who present in the clinic are diagnosed with primary melanoma, yet large-scale sequencing efforts have focused primarily on...