Marie-Laure Rives
Overview
Explore the profile of Marie-Laure Rives including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
873
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0
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Recent Articles
1.
Babbe H, Sundberg T, Tichenor M, Seierstad M, Bacani G, Berstler J, et al.
Proc Natl Acad Sci U S A
. 2023 Dec;
121(1):e2307086120.
PMID: 38147543
The salt-inducible kinases (SIK) 1-3 are key regulators of pro- versus anti-inflammatory cytokine responses during innate immune activation. The lack of highly SIK-family or SIK isoform-selective inhibitors suitable for repeat,...
2.
Wang J, Nakafuku K, Ziff J, Gelin C, Gholami H, Thompson A, et al.
Bioorg Med Chem Lett
. 2023 Oct;
96:129492.
PMID: 37778428
Natural killer group 2D (NKG2D) is a homodimeric activating immunoreceptor whose function is to detect and eliminate compromised cells upon binding to the NKG2D ligands (NKG2DL) major histocompatibility complex (MHC)...
3.
Stalewski J, Shih A, Papazyan R, Ramirez J, Ibanez G, Hsiao P, et al.
J Pharmacol Exp Ther
. 2023 May;
386(1):35-44.
PMID: 37142444
Inflammatory bowel disease (IBD) is characterized by chronic mucosal inflammation of the gastrointestinal tract and is associated with extracellular acidification of mucosal tissue. Several extracellular pH-sensing receptors, including G protein-coupled...
4.
Thompson A, Harbut M, Kung P, Karpowich N, Branson J, Grant J, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(18):e2216342120.
PMID: 37098070
NKG2D (natural-killer group 2, member D) is a homodimeric transmembrane receptor that plays an important role in NK, γδ, and CD8 T cell-mediated immune responses to environmental stressors such as...
5.
Patch R, Zhang R, Edavettal S, Macielag M, Eckardt A, Li J, et al.
Eur J Med Chem
. 2022 Apr;
236:114330.
PMID: 35436670
Pramlintide is an equipotent amylin analogue that reduces food intake and body weight in obese subjects and has been clinically approved as an adjunctive therapy for the treatment of adult...
6.
Damm-Ganamet K, Rives M, Wickenden A, McAllister H, Mirzadegan T
J Biol Chem
. 2020 Feb;
295(13):4359-4366.
PMID: 32079674
Excitatory amino acid transporters (EAATs) represent a protein family that is an emerging drug target with great therapeutic potential for managing central nervous system disorders characterized by dysregulation of glutamatergic...
7.
Miles L, Hermans S, Crespi G, Gooi J, Doughty L, Nero T, et al.
iScience
. 2019 Aug;
19:110-118.
PMID: 31369984
Polymorphism in the microglial receptor CD33 gene has been linked to late-onset Alzheimer disease (AD), and reduced expression of the CD33 sialic acid-binding domain confers protection. Thus, CD33 inhibition might...
8.
Rives M, Rady B, Swanson N, Zhao S, Qi J, Arnoult E, et al.
Mol Pharmacol
. 2018 Mar;
93(6):581-591.
PMID: 29572336
GPR40 is a clinically validated molecular target for the treatment of diabetes. Many GPR40 agonists have been identified to date, with the partial agonist fasiglifam (TAK-875) reaching phase III clinical...
9.
Rives M, Javitch J, Wickenden A
Biochem Pharmacol
. 2017 Feb;
135:1-11.
PMID: 28214518
Maintaining the integrity of cellular membranes is critical to protecting metabolic activities and genetic information from the environment. Regulation of transport across membranes of essential chemicals, including water, nutrients, hormones...
10.
Rives M, Shaw M, Zhu B, Hinke S, Wickenden A
Mol Pharmacol
. 2016 Nov;
90(6):766-774.
PMID: 27754898
In the liver, citrate is a key metabolic intermediate involved in the regulation of glycolysis and lipid synthesis and reduced expression of the hepatic citrate SLC13A5 transporter has been shown...