Maria Sadiq
Overview
Explore the profile of Maria Sadiq including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
67
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0
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Recent Articles
1.
Ibrahim A, Batlle E, Sneha S, Jimenez R, Pequerul R, Pares X, et al.
J Med Chem
. 2022 Feb;
65(5):3833-3848.
PMID: 35212533
Aldehyde dehydrogenases (ALDHs) are overexpressed in various tumor types including prostate cancer and considered a potential target for therapeutic intervention. 4-(Diethylamino)benzaldehyde (DEAB) has been extensively reported as a pan-inhibitor of...
2.
Presa D, Khurram S, Zubir A, Smarakan S, Cooper P, Morais G, et al.
Sci Rep
. 2021 Sep;
11(1):18930.
PMID: 34556703
Epidemiological studies have shown that head and neck cancer (HNC) is a complex multistage process that in part involves exposure to a combination of carcinogens and the capacity of certain...
3.
Quattrini L, Sadiq M, Petrarolo G, Maitland N, Frame F, Pors K, et al.
Biomedicines
. 2020 Dec;
8(12).
PMID: 33291762
Prostate cancer represents the most common malignancy diagnosed in men, and is the second-leading cause of cancer death in this population. In spite of dedicated efforts, the current therapies are...
4.
Allison S, Sadiq M, Baronou E, Cooper P, Dunnill C, Georgopoulos N, et al.
Cancer Lett
. 2018 Jun;
431:247.
PMID: 29934232
No abstract available.
5.
Errington R, Sadiq M, Cosentino L, Wiltshire M, Sadiq O, Sini M, et al.
Bioorg Med Chem Lett
. 2018 Mar;
28(8):1274-1277.
PMID: 29576510
Structural features from the anticancer prodrug nemorubicin (MMDX) and the DNA-binding molecule DRAQ5™ were used to prepare anthraquinone-based compounds, which were assessed for their potential to interrogate cytochrome P450 (CYP)...
6.
Pippione A, Giraudo A, Bonanni D, Carnovale I, Marini E, Cena C, et al.
Eur J Med Chem
. 2017 Sep;
139:936-946.
PMID: 28881288
The aldo-keto reductase 1C3 isoform (AKR1C3) plays a vital role in the biosynthesis of androgens, making this enzyme an attractive target for castration-resistant prostate cancer therapy. Although AKR1C3 is a...
7.
Allison S, Sadiq M, Baronou E, Cooper P, Dunnill C, Georgopoulos N, et al.
Cancer Lett
. 2017 Jun;
403:98-107.
PMID: 28624622
Organometallic complexes offer the prospect of targeting multiple pathways that are important in cancer biology. Here, the preclinical activity and mechanism(s) of action of a silver-bis(N-heterocyclic carbine) complex (Ag8) were...
8.
Elkashef S, Allison S, Sadiq M, Basheer H, Morais G, Loadman P, et al.
Sci Rep
. 2016 Sep;
6:33026.
PMID: 27611649
Polysialic acid (polySia) is a unique carbohydrate polymer expressed on the surface of NCAM (neuronal cell adhesion molecule) in a number of cancers where it modulates cell-cell and cell-matrix adhesion,...