Nikolaos T Georgopoulos
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Explore the profile of Nikolaos T Georgopoulos including associated specialties, affiliations and a list of published articles.
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23
Citations
651
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Recent Articles
1.
Peake M, Dunnill C, Ibraheem K, Smith A, Clarke D, Georgopoulos N
Front Bioeng Biotechnol
. 2024 Apr;
12:1386896.
PMID: 38646012
Autologous cell suspension (ACS)-based therapy represents a highly promising approach for burns and chronic wounds. However, existing technologies have not achieved the desired clinical success due to several limitations. To...
2.
Ibraheem K, Yhmed A, Nasef M, Georgopoulos N
Cells
. 2022 Oct;
11(20).
PMID: 36291141
The capacity to induce tumour-cell specific apoptosis represents the most unique feature of the TNF receptor (TNFR) family member CD40. Recent studies on the signalling events triggered by its membrane-presented...
3.
Ibraheem K, Dunnill C, Ioannou M, Mohamed A, Albarbar B, Georgopoulos N
Bio Protoc
. 2021 Aug;
8(13):e2907.
PMID: 34395739
One fundamental property of the TNR receptor (TNFR) family relates to how 'signal quality' (the extent of receptor ligation or cross-linking) influences the outcome of receptor ligation, for instance the...
4.
Dunnill C, Ibraheem K, Peake M, Ioannou M, Palmer M, Smith A, et al.
PLoS One
. 2020 Oct;
15(10):e0240454.
PMID: 33057448
Chemotherapy-induced alopecia (CIA) represents the most distressing side-effect for cancer patients. Scalp cooling is currently the only treatment to combat CIA, yet little is known about its cytoprotective effects in...
5.
Ibraheem K, Yhmed A, Qayyum T, Bryan N, Georgopoulos N
Cell Death Discov
. 2019 Dec;
5:148.
PMID: 31815003
A unique feature of CD40 among the TNF receptor (TNFR) superfamily is its exquisitely contextual effects, as originally demonstrated in normal and malignant B-lymphocytes. We studied renal cell carcinoma (RCC)...
6.
Allison S, Sadiq M, Baronou E, Cooper P, Dunnill C, Georgopoulos N, et al.
Cancer Lett
. 2018 Jun;
431:247.
PMID: 29934232
No abstract available.
7.
Allison S, Sadiq M, Baronou E, Cooper P, Dunnill C, Georgopoulos N, et al.
Cancer Lett
. 2017 Jun;
403:98-107.
PMID: 28624622
Organometallic complexes offer the prospect of targeting multiple pathways that are important in cancer biology. Here, the preclinical activity and mechanism(s) of action of a silver-bis(N-heterocyclic carbine) complex (Ag8) were...
8.
Baker S, Shabir S, Georgopoulos N, Southgate J
Am J Pathol
. 2016 Mar;
186(5):1267-77.
PMID: 27001627
Recreational abuse of ketamine has been associated with the emergence of a new bladder pain syndrome, ketamine-induced cystitis, characterized by chronic inflammation and urothelial ulceration. We investigated the direct effects...
9.
Dunnill C, Patton T, Brennan J, Barrett J, Dryden M, Cooke J, et al.
Int Wound J
. 2015 Dec;
14(1):89-96.
PMID: 26688157
Reactive oxygen species (ROS) play a pivotal role in the orchestration of the normal wound-healing response. They act as secondary messengers to many immunocytes and non-lymphoid cells, which are involved...
10.
Albarbar B, Dunnill C, Georgopoulos N
Cytokine Growth Factor Rev
. 2015 Jun;
26(6):659-71.
PMID: 26028499
The role of TNFR family members in regulating cell fate both in the immune system and in non-lymphoid tissues has been under extensive research for decades. Moreover, the ability of...