Marco Siderius
Overview
Explore the profile of Marco Siderius including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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Articles
49
Citations
830
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0
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Recent Articles
1.
Di Niro L, Linders A, Glynn T, Pegtel D, Siderius M, Crudden C, et al.
Extracell Vesicles Circ Nucl Acids
. 2024 Dec;
5(2):233-248.
PMID: 39698539
Dysregulated intercellular communication is a key feature driving cancer progression. Recently, extracellular vesicles (EVs) have added a new channel to this dense communication network. Despite solid evidence that EVs are...
2.
Perez Almeria C, Otun O, Schlimgen R, Lamme T, Crudden C, Youssef N, et al.
bioRxiv
. 2024 Nov;
PMID: 39574661
Chemokine stimulation of atypical chemokine receptor 3 (ACKR3) does not activate G proteins but recruits arrestins. It is a chemokine scavenger that indirectly influences responses by restricting the availability of...
3.
Anbuhl S, Dervillez X, Neubacher S, Schriek A, Bobkov V, de Taeye S, et al.
Biochem Pharmacol
. 2024 Aug;
227:116457.
PMID: 39098732
The chemokine receptor CXCR4 is involved in the development and migration of stem and immune cells but is also implicated in tumor progression and metastasis for a variety of cancers....
4.
Bergkamp N, van Senten J, Brink H, Bebelman M, van den Bor J, Cobanoglu T, et al.
Sci Signal
. 2023 Aug;
16(798):eade6737.
PMID: 37582160
The G protein-coupled receptor (GPCR) US28 encoded by the human cytomegalovirus (HCMV) is associated with accelerated progression of glioblastomas, aggressive brain tumors with a generally poor prognosis. Here, we showed...
5.
Bebelman M, Setiawan I, Bergkamp N, van Senten J, Crudden C, Bebelman J, et al.
iScience
. 2023 Aug;
26(8):107412.
PMID: 37575190
The human cytomegalovirus (HCMV)-encoded chemokine receptor US28 contributes to various aspects of the viral life cycle and promotes immune evasion by scavenging chemokines from the microenvironment of HCMV-infected cells. In...
6.
Zheng Y, van den Kerkhof M, van der Meer T, Gul S, Kuzikov M, Ellinger B, et al.
J Med Chem
. 2023 Jul;
66(15):10252-10264.
PMID: 37471520
Human African Trypanosomiasis (HAT), caused by , is one of the neglected tropical diseases with a continuing need for new medication. We here describe the discovery of 5-phenylpyrazolopyrimidinone analogs as...
7.
NanoB to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET
van den Bor J, Bergkamp N, Anbuhl S, Dekker F, Comez D, Perez Almeria C, et al.
Cell Rep Methods
. 2023 Apr;
3(3):100422.
PMID: 37056381
The therapeutic potential of ligands targeting disease-associated membrane proteins is predicted by ligand-receptor binding constants, which can be determined using NanoLuciferase (NanoLuc)-based bioluminescence resonance energy transfer (NanoBRET) methods. However, the...
8.
Zheng Y, Schroeder S, Kanev G, Botros S, William S, Sabra A, et al.
Int J Mol Sci
. 2023 Apr;
24(7).
PMID: 37047792
Schistosomiasis is a neglected tropical disease with high morbidity. Recently, the phosphodiesterase SmPDE4A was suggested as a putative new drug target. To support SmPDE4A targeted drug discovery, we cloned, isolated,...
9.
Brink H, van Senten J, De Vries-van Leeuwen I, da Costa Pereira D, Piersma S, Jimenez C, et al.
ACS Chem Biol
. 2022 Oct;
17(11):2972-2978.
PMID: 36255265
The cancerous inhibitor of protein phosphatase 2A (CIP2A) is an oncoprotein found overexpressed in many types of cancer. CIP2A has been shown to stabilize oncoproteins such as cMYC by shielding...
10.
Zheng Y, Muller J, Kunz S, Siderius M, Maes L, Caljon G, et al.
Int J Parasitol Drugs Drug Resist
. 2022 Jun;
19:47-55.
PMID: 35716585
As there is a continuous need for novel anti-infectives, the present study aimed to fuse two modes of action into a novel 3-nitroimidazo[1,2-b]pyridazine scaffold to improve antiparasitic efficacy. For this...