Marco A Di Grappa
Overview
Explore the profile of Marco A Di Grappa including associated specialties, affiliations and a list of published articles.
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11
Citations
673
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Recent Articles
1.
Han K, Leung E, Barbera L, Barnes E, Croke J, Di Grappa M, et al.
JCO Precis Oncol
. 2022 Feb;
2:1-8.
PMID: 35135145
Purpose: To determine whether plasma human papillomavirus (HPV) DNA predates clinical recurrence and compare its accuracy with 3-month fluorodeoxyglucose positron emission tomography (FDG-PET) in locally advanced cervical cancer. Methods: This...
2.
Muhanna N, Eu D, Chan H, Douglas C, Townson J, Di Grappa M, et al.
BMC Cancer
. 2021 Oct;
21(1):1075.
PMID: 34600526
Background: Monitoring circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs), known as liquid biopsies, continue to be developed as diagnostic and prognostic markers for a wide variety of cancer...
3.
Muhanna N, Di Grappa M, Chan H, Khan T, Jin C, Zheng Y, et al.
Sci Rep
. 2017 Dec;
7(1):16723.
PMID: 29196748
In cancer patients, circulating tumour-derived DNA (ctDNA) levels imperfectly reflect disease burden apparent on medical imaging. Further evaluation of ctDNA levels over time is needed to better understand the correlation...
4.
Chen Y, Di Grappa M, Molyneux S, McKee T, Waterhouse P, Penninger J, et al.
Sci Transl Med
. 2015 Dec;
7(317):317ra197.
PMID: 26659571
Osteosarcoma (OS) is the most common primary bone cancer, which occurs primarily in children and adolescents, severely affecting survivors' quality of life. Despite its chemosensitivity and treatment advances, long-term survival...
5.
Joshi P, Waterhouse P, Kannan N, Narala S, Fang H, Di Grappa M, et al.
Stem Cell Reports
. 2015 Jun;
5(1):31-44.
PMID: 26095608
Systemic and local signals must be integrated by mammary stem and progenitor cells to regulate their cyclic growth and turnover in the adult gland. Here, we show RANK-positive luminal progenitors...
6.
Wei L, Xu Y, Nelles E, Furlonger C, Wang J, Di Grappa M, et al.
J Cell Mol Med
. 2013 Nov;
17(11):1465-74.
PMID: 24251770
Interleukin (IL)-12 is the key cytokine in the initiation of a Th1 response and has shown promise as an anti-cancer agent; however, clinical trials involving IL-12 have been unsuccessful due...
7.
Joshi P, Di Grappa M, Khokha R
Trends Endocrinol Metab
. 2012 May;
23(6):299-309.
PMID: 22613704
Adult stem cells are recruited in response to specific physiological demands to regenerate, repair or maintain essential cellular components of tissues, while preserving self-renewal capacity. Signals that activate adult stem...
8.
Beristain A, Narala S, Di Grappa M, Khokha R
J Cell Sci
. 2012 Mar;
125(Pt 4):943-55.
PMID: 22421365
RANKL (receptor activator of NF-κB ligand) is a crucial cytokine for regulating diverse biological systems such as innate immunity, bone homeostasis and mammary gland differentiation, operating through activation of its...
9.
Molyneux S, Di Grappa M, Beristain A, McKee T, Wai D, Paderova J, et al.
J Clin Invest
. 2010 Aug;
120(9):3310-25.
PMID: 20697156
Some cancers have been stratified into subclasses based on their unique involvement of specific signaling pathways. The mapping of human cancer genomes is revealing a vast number of somatic alterations;...
10.
Murthy A, Defamie V, Smookler D, Di Grappa M, Horiuchi K, Federici M, et al.
J Clin Invest
. 2010 Jul;
120(8):2731-44.
PMID: 20628198
The cell death receptor Fas plays a role in the establishment of fulminant hepatitis, a major cause of drug-induced liver failure. Fas activation elicits extrinsic apoptotic and hepatoprotective signals; however,...