Marc Vendrell
Overview
Explore the profile of Marc Vendrell including associated specialties, affiliations and a list of published articles.
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Articles
114
Citations
1670
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0
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Recent Articles
1.
Nadal-Bufi F, Salomon P, de Moliner F, Sarris K, Wang Z, Wills R, et al.
J Am Chem Soc
. 2025 Feb;
147(9):7578-7587.
PMID: 39965918
Antibody-drug conjugates (ADCs) represent promising therapeutic constructs to enhance the selective delivery of drugs to target cells; however, attaining precise control over the timing and location of payload release remains...
2.
Wong M, Karmakar U, Bertolini M, Reese A, Mendive-Tapia L, Vendrell M
Chem Sci
. 2025 Feb;
16(10):4360-4365.
PMID: 39911336
Photocatalysts are excellent scaffolds for the light-mediated control of bioactive molecules. Current photocatalytic structures are not compatible with genetic encoding and therefore cannot be directly incorporated into the sequences of...
3.
Huang R, Qiao Q, Seah D, Shen T, Wu X, de Moliner F, et al.
J Am Chem Soc
. 2025 Feb;
147(6):5258-5268.
PMID: 39901830
Organic fluorophores with near-infrared (NIR) emission and reduced molecular size are crucial for advancing bioimaging and biosensing technologies. Traditional methods, such as conjugation expansion and heteroatom engineering, often fail to...
4.
Nadal-Bufi F, Nithun R, de Moliner F, Lin X, Habiballah S, Jbara M, et al.
ACS Cent Sci
. 2025 Jan;
11(1):66-75.
PMID: 39866693
The cellular uptake routes of peptides and proteins are complex and diverse, often handicapping therapeutic success. Understanding their mechanisms of internalization requires chemical derivatization with approaches that are compatible with...
5.
Kim J, Xu Y, Lim J, Lee J, Li M, Fox J, et al.
J Am Chem Soc
. 2024 Nov;
147(1):701-712.
PMID: 39614812
The revolutionary impact of photoredox catalytic processes has ignited novel avenues for exploration, empowering us to delve into nature in unprecedented ways and to pioneer innovative biotechnologies for therapy and...
6.
Nestoros E, Sharma A, Kim E, Kim J, Vendrell M
Nat Rev Chem
. 2024 Nov;
9(1):46-60.
PMID: 39506088
Photodynamic therapy (PDT) - which combines light, oxygen and photosensitizers (PS) to generate reactive oxygen species - has emerged as an effective approach for targeted ablation of pathogenic cells with...
7.
Geddis A, Mendive-Tapia L, Sujantho A, Liu E, McAughtrie S, Goodwin R, et al.
Anal Chem
. 2024 Oct;
96(45):17978-17983.
PMID: 39472080
Dysregulation of receptor tyrosine kinases (RTKs) has been shown to correlate with cancer cell proliferation and drug resistance. Thus, monitoring the activity of RTKs at a chemical level could provide...
8.
Bertolini M, Mendive-Tapia L, Karmakar U, Vendrell M
J Am Chem Soc
. 2024 Oct;
146(44):30565-30572.
PMID: 39441736
Drug resistance in B cell leukemia is characterized by the coexpression of CXCR5 and CXCR3 chemokine receptors, making it a valuable biomarker for patient stratification. Herein, we report a novel...
9.
Kuru E, Rittichier J, de Puig H, Flores A, Rout S, Han I, et al.
Nat Commun
. 2024 Sep;
15(1):7531.
PMID: 39237489
Binding-activated optical sensors are powerful tools for imaging, diagnostics, and biomolecular sensing. However, biosensor discovery is slow and requires tedious steps in rational design, screening, and characterization. Here we report...
10.
Nestoros E, de Moliner F, Nadal-Bufi F, Seah D, Ortega-Liebana M, Cheng Z, et al.
Nat Commun
. 2024 Sep;
15(1):7689.
PMID: 39227575
Controlling the succession of chemical processes with high specificity in complex systems is advantageous for widespread applications, from biomedical research to drug manufacturing. Despite synthetic advances in bioorthogonal and photochemical...