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Lorena Mendive-Tapia

Explore the profile of Lorena Mendive-Tapia including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 475
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Recent Articles
1.
Wong M, Karmakar U, Bertolini M, Reese A, Mendive-Tapia L, Vendrell M
Chem Sci . 2025 Feb; 16(10):4360-4365. PMID: 39911336
Photocatalysts are excellent scaffolds for the light-mediated control of bioactive molecules. Current photocatalytic structures are not compatible with genetic encoding and therefore cannot be directly incorporated into the sequences of...
2.
Morris K, Bulovaite E, Kaizuka T, Schnorrenberg S, Adams C, Komiyama N, et al.
Elife . 2024 Nov; 13. PMID: 39570289
The concept that dimeric protein complexes in synapses can sequentially replace their subunits has been a cornerstone of Francis Crick's 1984 hypothesis, explaining how long-term memories could be maintained in...
3.
Geddis A, Mendive-Tapia L, Sujantho A, Liu E, McAughtrie S, Goodwin R, et al.
Anal Chem . 2024 Oct; 96(45):17978-17983. PMID: 39472080
Dysregulation of receptor tyrosine kinases (RTKs) has been shown to correlate with cancer cell proliferation and drug resistance. Thus, monitoring the activity of RTKs at a chemical level could provide...
4.
Bertolini M, Mendive-Tapia L, Karmakar U, Vendrell M
J Am Chem Soc . 2024 Oct; 146(44):30565-30572. PMID: 39441736
Drug resistance in B cell leukemia is characterized by the coexpression of CXCR5 and CXCR3 chemokine receptors, making it a valuable biomarker for patient stratification. Herein, we report a novel...
5.
Bertolini M, Mendive-Tapia L, Ghashghaei O, Reese A, Lochenie C, Schoepf A, et al.
ACS Cent Sci . 2024 May; 10(5):969-977. PMID: 38799658
Immunosuppressants are clinically approved drugs to treat the potential rejection of transplanted organs and require frequent monitoring due to their narrow therapeutic window. Immunophilins are small proteins that bind immunosuppressants...
6.
Cheng Z, Benson S, Mendive-Tapia L, Nestoros E, Lochenie C, Seah D, et al.
Angew Chem Int Ed Engl . 2024 May; 63(30):e202404587. PMID: 38717316
Photodynamic therapy is an anti-cancer treatment that requires illumination of photosensitizers to induce local cell death. Current near-infrared organic photosensitizers are built from large and non-modular structures that cannot be...
7.
Mendive-Tapia L, Miret-Casals L, Barth N, Wang J, De Bray A, Beltramo M, et al.
Angew Chem Weinheim Bergstr Ger . 2024 Mar; 135(20):e202302688. PMID: 38516305
The G protein-coupled kisspeptin receptor (GPR54 or KISS1R) is an important mediator in reproduction, metabolism and cancer biology; however, there are limited fluorescent probes or antibodies for direct imaging of...
8.
Cheng Z, Thompson E, Mendive-Tapia L, Scott J, Benson S, Kitamura T, et al.
Angew Chem Weinheim Bergstr Ger . 2024 Mar; 135(8):e202216142. PMID: 38515764
Cytotoxic immune cells, including T lymphocytes (CTLs) and natural killer (NK) cells, are essential components of the host response against tumors. CTLs and NK cells secrete granzyme A (GzmA) upon...
9.
de Moliner F, Konieczna Z, Mendive-Tapia L, Saleeb R, Morris K, Gonzalez-Vera J, et al.
Angew Chem Weinheim Bergstr Ger . 2024 Mar; 135(4):e202216231. PMID: 38515539
The multiple applications of super-resolution microscopy have prompted the need for minimally invasive labeling strategies for peptide-guided fluorescence imaging. Many fluorescent reporters display limitations (e.g., large and charged scaffolds, non-specific...
10.
Barth N, Mendive-Tapia L, Subiros-Funosas R, Ghashghaei O, Lavilla R, Maiorino L, et al.
Angew Chem Weinheim Bergstr Ger . 2024 Mar; 134(5):e202113020. PMID: 38505298
The detection and quantification of apoptotic cells is a key process in cancer research, particularly during the screening of anticancer therapeutics and in mechanistic studies using preclinical models. Intravital optical...