Fabio de Moliner
Overview
Explore the profile of Fabio de Moliner including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
310
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0
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Recent Articles
1.
Nadal-Bufi F, Salomon P, de Moliner F, Sarris K, Wang Z, Wills R, et al.
J Am Chem Soc
. 2025 Feb;
147(9):7578-7587.
PMID: 39965918
Antibody-drug conjugates (ADCs) represent promising therapeutic constructs to enhance the selective delivery of drugs to target cells; however, attaining precise control over the timing and location of payload release remains...
2.
Huang R, Qiao Q, Seah D, Shen T, Wu X, de Moliner F, et al.
J Am Chem Soc
. 2025 Feb;
147(6):5258-5268.
PMID: 39901830
Organic fluorophores with near-infrared (NIR) emission and reduced molecular size are crucial for advancing bioimaging and biosensing technologies. Traditional methods, such as conjugation expansion and heteroatom engineering, often fail to...
3.
Nadal-Bufi F, Nithun R, de Moliner F, Lin X, Habiballah S, Jbara M, et al.
ACS Cent Sci
. 2025 Jan;
11(1):66-75.
PMID: 39866693
The cellular uptake routes of peptides and proteins are complex and diverse, often handicapping therapeutic success. Understanding their mechanisms of internalization requires chemical derivatization with approaches that are compatible with...
4.
Kuru E, Rittichier J, de Puig H, Flores A, Rout S, Han I, et al.
Nat Commun
. 2024 Sep;
15(1):7531.
PMID: 39237489
Binding-activated optical sensors are powerful tools for imaging, diagnostics, and biomolecular sensing. However, biosensor discovery is slow and requires tedious steps in rational design, screening, and characterization. Here we report...
5.
Nestoros E, de Moliner F, Nadal-Bufi F, Seah D, Ortega-Liebana M, Cheng Z, et al.
Nat Commun
. 2024 Sep;
15(1):7689.
PMID: 39227575
Controlling the succession of chemical processes with high specificity in complex systems is advantageous for widespread applications, from biomedical research to drug manufacturing. Despite synthetic advances in bioorthogonal and photochemical...
6.
de Moliner F, Nadal-Bufi F, Vendrell M
Curr Opin Chem Biol
. 2024 Apr;
80:102458.
PMID: 38670028
Fluorescent probes have revolutionized biological imaging by enabling the real-time visualization of cellular processes under physiological conditions. However, their size and potential perturbative nature can pose challenges in retaining the...
7.
de Moliner F, Konieczna Z, Mendive-Tapia L, Saleeb R, Morris K, Gonzalez-Vera J, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
135(4):e202216231.
PMID: 38515539
The multiple applications of super-resolution microscopy have prompted the need for minimally invasive labeling strategies for peptide-guided fluorescence imaging. Many fluorescent reporters display limitations (e.g., large and charged scaffolds, non-specific...
8.
de Moliner F, Knox K, Gordon D, Lee M, Tipping W, Geddis A, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
133(14):7715-7720.
PMID: 38505234
Sucrose is the main saccharide used for long-distance transport in plants and plays an essential role in energy metabolism; however, there are no analogues for real-time imaging in live cells....
9.
Reese A, de Moliner F, Mendive-Tapia L, Benson S, Kuru E, Bridge T, et al.
ACS Cent Sci
. 2024 Jan;
10(1):143-154.
PMID: 38292608
The essential functions that cytokine/immune cell interactions play in tissue homeostasis and during disease have prompted the molecular design of targeted fluorophores to monitor their activity in real time. Whereas...
10.
Gidden Z, Oi C, Johnston E, Konieczna Z, Bhaskar H, Mendive-Tapia L, et al.
Nano Lett
. 2023 Nov;
23(22):10633-10641.
PMID: 37916770
Fluorescence microscopy enables specific visualization of proteins in living cells and has played an important role in our understanding of the protein subcellular location and function. Some proteins, however, show...