Marc Vendrell
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Explore the profile of Marc Vendrell including associated specialties, affiliations and a list of published articles.
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114
Citations
1670
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Recent Articles
11.
Mach L, Omran A, Bouma J, Radetzki S, Sykes D, Guba W, et al.
J Med Chem
. 2024 Jul;
67(14):11841-11867.
PMID: 38990855
The cannabinoid receptor type 1 (CBR) is pivotal within the endocannabinoid system regulating various signaling cascades with effects in appetite regulation, pain perception, memory formation, and thermoregulation. Still, understanding of...
12.
Bertolini M, Mendive-Tapia L, Ghashghaei O, Reese A, Lochenie C, Schoepf A, et al.
ACS Cent Sci
. 2024 May;
10(5):969-977.
PMID: 38799658
Immunosuppressants are clinically approved drugs to treat the potential rejection of transplanted organs and require frequent monitoring due to their narrow therapeutic window. Immunophilins are small proteins that bind immunosuppressants...
13.
Lochenie C, Duncan S, Zhou Y, Fingerhut L, Kiang A, Benson S, et al.
Adv Mater
. 2024 May;
36(31):e2404107.
PMID: 38762778
The emergence of multidrug resistant (MDR) pathogens and the scarcity of new potent antibiotics and antifungals are one of the biggest threats to human health. Antimicrobial photodynamic therapy (aPDT) combines...
14.
Senan-Salinas A, Comas L, Esteban P, Garzon-Tituana M, Cheng Z, Santiago L, et al.
ACS Pharmacol Transl Sci
. 2024 May;
7(5):1474-1484.
PMID: 38751645
Granzymes (Gzms), a family of serine proteases, expressed by immune and nonimmune cells, present perforin-dependent and independent intracellular and extracellular functions. When released in the extracellular space, GzmA, with trypsin-like...
15.
Cheng Z, Benson S, Mendive-Tapia L, Nestoros E, Lochenie C, Seah D, et al.
Angew Chem Int Ed Engl
. 2024 May;
63(30):e202404587.
PMID: 38717316
Photodynamic therapy is an anti-cancer treatment that requires illumination of photosensitizers to induce local cell death. Current near-infrared organic photosensitizers are built from large and non-modular structures that cannot be...
16.
de Moliner F, Nadal-Bufi F, Vendrell M
Curr Opin Chem Biol
. 2024 Apr;
80:102458.
PMID: 38670028
Fluorescent probes have revolutionized biological imaging by enabling the real-time visualization of cellular processes under physiological conditions. However, their size and potential perturbative nature can pose challenges in retaining the...
17.
Mendive-Tapia L, Miret-Casals L, Barth N, Wang J, De Bray A, Beltramo M, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
135(20):e202302688.
PMID: 38516305
The G protein-coupled kisspeptin receptor (GPR54 or KISS1R) is an important mediator in reproduction, metabolism and cancer biology; however, there are limited fluorescent probes or antibodies for direct imaging of...
18.
Nadal Rodriguez P, Ghashghaei O, Schoepf A, Benson S, Vendrell M, Lavilla R
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
135(41):e202303889.
PMID: 38516006
Charting the chemical reaction space around the combination of carbonyls, amines, and isocyanoacetates allows the description of new multicomponent processes leading to a variety of unsaturated imidazolone scaffolds. The resulting...
19.
Cheng Z, Thompson E, Mendive-Tapia L, Scott J, Benson S, Kitamura T, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
135(8):e202216142.
PMID: 38515764
Cytotoxic immune cells, including T lymphocytes (CTLs) and natural killer (NK) cells, are essential components of the host response against tumors. CTLs and NK cells secrete granzyme A (GzmA) upon...
20.
de Moliner F, Konieczna Z, Mendive-Tapia L, Saleeb R, Morris K, Gonzalez-Vera J, et al.
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
135(4):e202216231.
PMID: 38515539
The multiple applications of super-resolution microscopy have prompted the need for minimally invasive labeling strategies for peptide-guided fluorescence imaging. Many fluorescent reporters display limitations (e.g., large and charged scaffolds, non-specific...