Mar Martin-Fontecha
Overview
Explore the profile of Mar Martin-Fontecha including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
859
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Recent Articles
1.
Garrido-Garcia P, Quiros I, Milan-Rois P, Ortega-Gutierrez S, Martin-Fontecha M, Campos L, et al.
Nat Chem
. 2025 Feb;
PMID: 40000889
1,5-Disubstituted bicyclo[2.1.1]hexanes are bridged scaffolds with well-defined exit vectors that are becoming increasingly popular building blocks in medicinal chemistry because they are saturated bioisosteres of ortho-substituted phenyl rings. Here we...
2.
Ogulur I, Mitamura Y, Yazici D, Pat Y, Ardicli S, Li M, et al.
Cell Mol Immunol
. 2025 Feb;
22(3):211-242.
PMID: 39962262
Significant advancements have been made in understanding the cellular and molecular mechanisms of type 2 immunity in allergic diseases such as asthma, allergic rhinitis, chronic rhinosinusitis, eosinophilic esophagitis (EoE), food...
3.
Vazquez-Villa H, Rueda-Zubiaurre A, Fernandez D, Foronda R, Parker C, Cravatt B, et al.
Eur J Med Chem
. 2024 Dec;
283():117102.
PMID: 39616692
Honokiol is a natural product with an interesting array of biological effects, including significant anti-tumor properties. However, full exploration of its therapeutic potential is hampered by its modest pharmacokinetic profile...
4.
Benhamu B, Martin-Fontecha M, Vazquez-Villa H, Lopez-Rodriguez M, Ortega-Gutierrez S
Biomedicines
. 2022 Aug;
10(8).
PMID: 36009552
Aging is considered the main risk factor for many chronic diseases that frequently appear at advanced ages. However, the inevitability of this process is being questioned by recent research that...
5.
Andreu J, Huecas S, Araujo-Bazan L, Vazquez-Villa H, Martin-Fontecha M
Biomedicines
. 2022 Aug;
10(8).
PMID: 36009372
The global spread of bacterial antimicrobial resistance is associated to millions of deaths from bacterial infections per year, many of which were previously treatable. This, combined with slow antibiotic deployment,...
6.
Angelina A, Jimenez-Saiz R, Perez-Diego M, Maldonado A, Ruckert B, Akdis M, et al.
Clin Exp Allergy
. 2022 Jan;
52(4):540-549.
PMID: 34995385
Background: Cannabinoids are lipid-derived mediators with anti-inflammatory properties in different diseases. WIN55212-2, a non-selective synthetic cannabinoid, reduces immediate anaphylactic reactions in a mouse model of peanut allergy, but its capacity...
7.
Angelina A, Perez-Diego M, Maldonado A, Ruckert B, Akdis M, Martin-Fontecha M, et al.
Allergy
. 2021 Oct;
77(3):1029-1032.
PMID: 34713459
No abstract available.
8.
Angelina A, Perez-Diego M, Lopez-Abente J, Ruckert B, Nombela I, Akdis M, et al.
Mucosal Immunol
. 2021 Sep;
15(1):96-108.
PMID: 34548620
The generation of functional regulatory T cells (Tregs) is essential to keep tissue homeostasis and restore healthy immune responses in many biological and inflammatory contexts. Cannabinoids have been pointed out...
9.
Marcos-Ramiro B, Gil-Ordonez A, Marin-Ramos N, Ortega-Nogales F, Balabasquer M, Gonzalo P, et al.
ACS Cent Sci
. 2021 Sep;
7(8):1300-1310.
PMID: 34471675
Hutchinson-Gilford progeria syndrome (HGPS, progeria) is a rare genetic disease characterized by premature aging and death in childhood for which there were no approved drugs for its treatment until last...
10.
Huecas S, Araujo-Bazan L, Ruiz F, Ruiz-Avila L, Martinez R, Escobar-Pena A, et al.
J Med Chem
. 2021 Apr;
64(9):5730-5745.
PMID: 33908781
Bacterial resistance to antibiotics makes previously manageable infections again disabling and lethal, highlighting the need for new antibacterial strategies. In this regard, inhibition of the bacterial division process by targeting...