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Mar Martin-Fontecha

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Articles 42
Citations 859
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Recent Articles
11.
Angelina A, Martin-Fontecha M, Ruckert B, Wawrzyniak P, Perez-Diego M, Lopez-Abente J, et al.
Allergy . 2020 Dec; 76(6):1900-1902. PMID: 33319366
No abstract available.
12.
Marin-Ramos N, Balabasquer M, Ortega-Nogales F, Torrecillas I, Gil-Ordonez A, Marcos-Ramiro B, et al.
J Med Chem . 2019 Jun; 62(13):6035-6046. PMID: 31181882
Blockade of Ras activity by inhibiting its post-translational methylation catalyzed by isoprenylcysteine carboxylmethyltransferase (ICMT) has been suggested as a promising antitumor strategy. However, the paucity of inhibitors has precluded the...
13.
Manterola A, Bernal-Chico A, Cipriani R, Canedo-Antelo M, Moreno-Garcia A, Martin-Fontecha M, et al.
Biochem Pharmacol . 2018 Aug; 157:189-201. PMID: 30075103
Multiple sclerosis (MS) is a chronic demyelinating disease of unknown etiology in which tissue pathology suggests both immune-dependent attacks to oligodendroglia and primary oligodendrocyte demise. The endocannabinoid system has been...
14.
Gil-Ordonez A, Martin-Fontecha M, Ortega-Gutierrez S, Lopez-Rodriguez M
Biochem Pharmacol . 2018 Jul; 157:18-32. PMID: 30059673
Monoacylglycerol lipase (MAGL) has been characterized as the main enzyme responsible for the inactivation of the most abundant brain endocannabinoid, 2-arachidonoylglycerol (2-AG). Besides this role, MAGL has progressively acquired a...
15.
Hernandez-Torres G, Enriquez-Palacios E, Mecha M, Feliu A, Rueda-Zubiaurre A, Angelina A, et al.
Bioconjug Chem . 2018 May; 29(6):2021-2027. PMID: 29733594
Serotonin (5-HT) modulates key aspects of the immune system. However, its precise function and the receptors involved in the observed effects have remained elusive. Among the different serotonin receptors, 5-HT...
16.
Camicia F, Celentano A, Johns M, Chan J, Maldonado L, Vaca H, et al.
PLoS Negl Trop Dis . 2018 Feb; 12(2):e0006267. PMID: 29425245
Background: Cestodes are a diverse group of parasites, some of them being agents of neglected diseases. In cestodes, little is known about the functional properties of G protein coupled receptors...
17.
Martin-Fontecha M, Angelina A, Ruckert B, Rueda-Zubiaurre A, Martin-Cruz L, Veen W, et al.
Bioconjug Chem . 2018 Jan; 29(2):382-389. PMID: 29314831
The human endogenous cannabinoid system (ECS) regulates key physiological processes and alterations in its signaling pathways, and endocannabinoid levels are associated with diseases such as neurological and neuropsychiatric conditions, cancer,...
18.
Palomares O, Akdis M, Martin-Fontecha M, Akdis C
Immunol Rev . 2017 Jun; 278(1):219-236. PMID: 28658547
Allergy is a major public health problem with a high socio-economic impact. The number of allergic patients is expected to reach to four billion within two decades when the World's...
19.
Artola M, Ruiz-Avila L, Ramirez-Aportela E, Martinez R, Araujo-Bazan L, Vazquez-Villa H, et al.
Chem Sci . 2017 Jun; 8(2):1525-1534. PMID: 28616148
FtsZ is a widely conserved tubulin-like GTPase that directs bacterial cell division and a new target for antibiotic discovery. This protein assembly machine cooperatively polymerizes forming single-stranded filaments, by means...
20.
Gonzalez-Vera J, Medina R, Martin-Fontecha M, Gonzalez A, de la Fuente T, Vazquez-Villa H, et al.
Sci Rep . 2017 Jan; 7:41293. PMID: 28117458
Serotonin 5-HT receptor has been proposed as a promising therapeutic target for cognition enhancement though the development of new antagonists is still needed to validate these molecules as a drug...