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Manfred Nimtz

Explore the profile of Manfred Nimtz including associated specialties, affiliations and a list of published articles. Areas
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Articles 135
Citations 2975
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Recent Articles
1.
Esmaeeli M, Nimtz M, Jansch L, Ruddock L, Leimkuhler S
FEBS Lett . 2023 May; 597(13):1792-1801. PMID: 37247262
Human aldehyde oxidase (hAOX1) is a molybdoenzyme that oxidizes aldehydes and N-heterocyclic compounds, thereby generating hydrogen peroxide (H O ) and superoxide during turnover. hAOX1 has been shown previously to...
2.
Esmaeeli M, Nimtz M, Jansch L, Ruddock L, Leimkuhler S
Drug Metab Dispos . 2023 Apr; 51(6):764-770. PMID: 37012073
Human aldehyde oxidase (hAOX1) is a molybdoflavoenzyme that belongs to the xanthine oxidase (XO) family. hAOX1 is involved in phase I drug metabolism, but its physiologic role is not fully...
3.
Zakaria M, Stegemann T, Sievert C, Kruse L, Kaltenegger E, Girreser U, et al.
Plant Cell . 2022 Feb; 34(6):2364-2382. PMID: 35212762
Polyamines are important metabolites in plant development and abiotic and biotic stress responses. Copper-containing amine oxidases (CuAOs) are involved in the regulation of polyamine levels in the cell. CuAOs oxidize...
4.
Schubert M, Nimtz M, Bertoglio F, Schmelz S, Lukat P, van den Heuvel J
Methods Mol Biol . 2021 May; 2305:129-140. PMID: 33950387
The expression of mammalian recombinant proteins in insect cell lines using transient-plasmid-based gene expression enables the production of high-quality protein samples. Here, the procedure for virus-free transient gene expression (TGE)...
5.
Wiesselmann M, Hebecker S, Borrero-de Acuna J, Nimtz M, Bollivar D, Jansch L, et al.
Biochem J . 2020 Nov; 477(23):4635-4654. PMID: 33211085
During bacteriochlorophyll a biosynthesis, the oxygen-independent conversion of Mg-protoporphyrin IX monomethyl ester (Mg-PME) to protochlorophyllide (Pchlide) is catalyzed by the anaerobic Mg-PME cyclase termed BchE. Bioinformatics analyses in combination with...
6.
Zafar M, Jahan H, Shafeeq S, Nimtz M, Jansch L, Romling U, et al.
Infect Immun . 2020 Aug; 88(11). PMID: 32839186
Upon biofilm formation, production of extracellular matrix components and alteration in physiology and metabolism allows bacteria to build up multicellular communities which can facilitate nutrient acquisition during unfavorable conditions and...
7.
Li Z, Nimtz M, Rinas U
Eng Life Sci . 2020 Jul; 17(8):881-891. PMID: 32624836
The global proteome response toward recombinant protein production in BL21 (DE3) grown in complex and defined medium was analyzed. Overproduction of human basic fibroblast growth factor (hFGF-2), a difficult-to-fold protein,...
8.
Klunemann T, Nimtz M, Jansch L, Layer G, Blankenfeldt W
FEBS J . 2020 Apr; 288(1):244-261. PMID: 32255259
Certain facultative anaerobes such as the opportunistic human pathogen Pseudomonas aeruginosa can respire on nitrate, a process generally known as denitrification. This enables denitrifying bacteria to survive in anoxic environments...
9.
Antenucci F, Magnowska Z, Nimtz M, Roesch C, Jansch L, Bojesen A
Vet Microbiol . 2019 Aug; 235:188-194. PMID: 31383301
Outer membrane vesicles (OMVs) are produced and secreted virtually by every known Gram-negative bacterium. Despite their non-live nature, they share antigenic characteristics with the bacteria they originate from. This, together...
10.
Kamal S, Rybtke M, Nimtz M, Sperlein S, Giske C, Trcek J, et al.
Front Microbiol . 2019 Jul; 10:1372. PMID: 31338071
is an environmental bacterium and a nosocomial pathogen with clone C one of the most prevalent clonal groups. The clone C specific genomic island PACGI-1 harbors a xenolog of encoding...