Harald S Conradt
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Explore the profile of Harald S Conradt including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
309
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Recent Articles
1.
Costa J, Streich L, Pinto S, Pronto-Laborinho A, Nimtz M, Conradt H, et al.
Mol Neurobiol
. 2019 Jan;
56(8):5729-5739.
PMID: 30674035
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease for which the existing candidate biomarkers (neurofilaments) have low specificity. Changes in blood IgG N-glycosylation have been observed in several...
2.
Costa J, Gatermann M, Nimtz M, Kandzia S, Glatzel M, Conradt H
Anal Chem
. 2018 Jun;
90(13):7871-7879.
PMID: 29888905
Cells release vesicles to the surroundings, the extracellular vesicles (EVs), which may transmit biomolecules to other cells, and are found in bodily fluids, thus constituting emerging biomarker targets. Many studies...
3.
Goncalves M, Tillack L, de Carvalho M, Pinto S, Conradt H, Costa J
Clin Chim Acta
. 2014 Sep;
438:342-9.
PMID: 25261856
Background: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease of the motor neuron for which no clinically validated biomarkers have been identified. Methods: We have quantified by ELISA the...
4.
Escrevente C, Grammel N, Kandzia S, Zeiser J, Tranfield E, Conradt H, et al.
PLoS One
. 2013 Dec;
8(10):e78631.
PMID: 24302979
Exosomes consist of vesicles that are secreted by several human cells, including tumor cells and neurons, and they are found in several biological fluids. Exosomes have characteristic protein and lipid...
5.
Crusat M, Liu J, Palma A, Childs R, Liu Y, Wharton S, et al.
Virology
. 2013 Sep;
447(1-2):326-37.
PMID: 24050651
As avian influenza A(H5N1) viruses continue to circulate in Asia and Africa, global concerns of an imminent pandemic persist. Recent experimental studies suggest that efficient transmission between humans of current...
6.
Gouveia R, Schaffer L, Papp S, Grammel N, Kandzia S, Head S, et al.
Biochim Biophys Acta
. 2012 Sep;
1820(12):2007-19.
PMID: 23000574
Background: Several glycan structures are functionally relevant in biological events associated with differentiation and regeneration which occur in the central nervous system. Here we have analysed the glycogene expression and...
7.
Machado E, Kandzia S, Carilho R, Altevogt P, Conradt H, Costa J
Glycobiology
. 2010 Oct;
21(3):376-86.
PMID: 21030537
Ovarian carcinoma is the leading cause of death from gynecological cancers in many Western countries. Aberrant glycosylation is an important aspect in malignant transformation and consequently in ovarian cancer. In...
8.
Ceaglio N, Etcheverrigaray M, Conradt H, Grammel N, Kratje R, Oggero M
J Biotechnol
. 2010 Jan;
146(1-2):74-83.
PMID: 20067809
The type I human interferon alpha (hIFN-alpha) family consists of small proteins that exert a multiplicity of biological actions including antiviral, antiproliferative and immunomodulatory effects. However, though administration of recombinant...
9.
Gouveia R, Kandzia S, Conradt H, Costa J
J Biotechnol
. 2009 Nov;
145(2):130-8.
PMID: 19922746
L1 is a cell adhesion molecule that is heavily glycosylated and is essential for normal development of the central nervous system. In this work, we compare the N-glycosylation of the...
10.
Palma A, de Carvalho M, Grammel N, Pinto S, Barata N, Conradt H, et al.
Amyotroph Lateral Scler
. 2008 Jul;
9(6):339-49.
PMID: 18608108
In ALS, the identification of abnormal proteins in biological fluids might be useful for the understanding of the ethiopathogenesis of the disease. Furthermore, it can provide biomarkers useful for diagnosis,...