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Manabu Takahashi

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Articles 61
Citations 517
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Recent Articles
1.
Wakabayashi T, Takahashi M, Okazaki H, Okazaki S, Yokote K, Tada H, et al.
J Atheroscler Thromb . 2024 May; 31(7):1005-1023. PMID: 38710625
Familial hypobetalipoproteinemia (FHBL) 1 is a rare genetic disorder with an autosomal codominant mode of inheritance and is caused by defects in the apolipoprotein (apo) B (APOB) gene that disable...
2.
Takahashi M, Okazaki H, Tada H, Ishibashi S
J Clin Lipidol . 2023 Sep; 17(6):834-838. PMID: 37777472
Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder caused by mutations in the sterol 27-hydroxylase gene (CYP27A1). Due to the deficiency of 27-hydroxylase, the synthesis of bile acids from...
3.
Shibuya K, Ebihara K, Takahashi M, Kurashina T, Nagashima S, Okada K, et al.
JMA J . 2023 May; 6(2):216-219. PMID: 37179722
Multiple endocrine neoplasia type 1 (MEN1) is a rare genetic disorder, resulting from gene abnormalities, which causes tumors mainly in the endocrine glands. We experienced a sporadic case of MEN1...
4.
Asano T, Wakabayashi T, Kondo Y, Okada K, Yamamuro D, Koga Y, et al.
J Clin Lipidol . 2022 Dec; 17(1):78-86. PMID: 36522261
Background: 25-hydroxycholesterol (25HC), produced by cholesterol 25-hydroxylase (CH25H) in macrophages, has been reported to inhibit the replication of viral pathogens such as severe acute respiratory syndrome coronavirus-2. Also, CH25H expression...
5.
Bredefeld C, Hussain M, Averna M, Black D, Brin M, Burnett J, et al.
J Clin Lipidol . 2022 Oct; 16(6):797-812. PMID: 36243606
The Abetalipoproteinemia and Related Disorders Foundation was established in 2019 to provide guidance and support for the life-long management of inherited hypocholesterolemia disorders. Our mission is "to improve the lives...
6.
Kawabata N, Okada K, Ando A, Kurashina T, Takahashi M, Wakabayashi T, et al.
J Diabetes Investig . 2022 Aug; 13(12):1963-1970. PMID: 36039846
Aims/introduction: It remains to be fully elucidated whether nutrition education by dietitians can lead to specific positive changes in the food choices of patients with diabetes. Materials And Methods: A...
7.
Takahashi M, Yamamuro D, Wakabayashi T, Takei A, Takei S, Nagashima S, et al.
J Biol Chem . 2022 Aug; 298(9):102322. PMID: 35926714
During obesity, tissue macrophages increase in number and become proinflammatory, thereby contributing to metabolic dysfunction. Lipoprotein lipase (LPL), which hydrolyzes triglyceride in lipoproteins, is secreted by macrophages. However, the role...
8.
Hatano Y, Sawayama N, Miyashita H, Kurashina T, Okada K, Takahashi M, et al.
J Endocr Soc . 2022 Jul; 6(8):bvac098. PMID: 35822200
Context: The association between primary aldosteronism and obesity, especially its sex difference, remains unknown. Objective: To assess the association for each subtype of primary aldosteronism with obesity parameters including visceral...
9.
Takahashi M, Sotodate G, Kajiwara W
Cardiol Young . 2022 Jul; 33(3):493-495. PMID: 35801280
The Chiari network is an embryonic remnant of the right venosus, consisting of a thin, mobile structure connected to the right atrium. Neonates with the Chiari network may present with...
10.
Shibuya K, Ebihara K, Ebihara C, Sawayama N, Isoda M, Yamamuro D, et al.
J Biol Chem . 2022 Apr; 298(6):101936. PMID: 35430252
Valosin-containing protein (VCP) is a member of AAA-ATPase superfamily involved in various cellular functions. To investigate the pathophysiological role of VCP in metabolic disorders, we generated knock-in mice bearing an...