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Daisuke Yamamuro

Explore the profile of Daisuke Yamamuro including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 150
Followers 0
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Recent Articles
1.
Muramatsu T, Yamamuro D, Kushiyama A, Kikuchi T
J Diabetes Investig . 2024 Nov; 16(2):225-235. PMID: 39531008
Aims/introduction: We investigated the association between the ankle reflex and the estimated glomerular filtration rate (eGFR) in patients with type 2 diabetes. Materials And Methods: This was a single-center, retrospective,...
2.
Yamada N, Karasawa T, Ito J, Yamamuro D, Morimoto K, Nakamura T, et al.
Nat Commun . 2024 Mar; 15(1):2195. PMID: 38472233
Recent evidence indicates ferroptosis is implicated in the pathophysiology of various liver diseases; however, the organ-specific regulation mechanism is poorly understood. Here, we demonstrate 7-dehydrocholesterol reductase (DHCR7), the terminal enzyme...
3.
Asano T, Wakabayashi T, Kondo Y, Okada K, Yamamuro D, Koga Y, et al.
J Clin Lipidol . 2022 Dec; 17(1):78-86. PMID: 36522261
Background: 25-hydroxycholesterol (25HC), produced by cholesterol 25-hydroxylase (CH25H) in macrophages, has been reported to inhibit the replication of viral pathogens such as severe acute respiratory syndrome coronavirus-2. Also, CH25H expression...
4.
Takahashi M, Yamamuro D, Wakabayashi T, Takei A, Takei S, Nagashima S, et al.
J Biol Chem . 2022 Aug; 298(9):102322. PMID: 35926714
During obesity, tissue macrophages increase in number and become proinflammatory, thereby contributing to metabolic dysfunction. Lipoprotein lipase (LPL), which hydrolyzes triglyceride in lipoproteins, is secreted by macrophages. However, the role...
5.
Shibuya K, Ebihara K, Ebihara C, Sawayama N, Isoda M, Yamamuro D, et al.
J Biol Chem . 2022 Apr; 298(6):101936. PMID: 35430252
Valosin-containing protein (VCP) is a member of AAA-ATPase superfamily involved in various cellular functions. To investigate the pathophysiological role of VCP in metabolic disorders, we generated knock-in mice bearing an...
6.
Isoda M, Ebihara K, Sawayama N, Murakami A, Ebihara C, Shibuya K, et al.
Sci Rep . 2021 Sep; 11(1):17691. PMID: 34489483
Leptin is an adipocyte-derived hormone that regulates appetite and energy expenditure via the hypothalamus. Since the majority of obese subjects are leptin resistant, leptin sensitizers, rather than leptin itself, are...
7.
Takei S, Nagashima S, Takei A, Yamamuro D, Wakabayashi T, Murakami A, et al.
Diabetes . 2020 Aug; 69(11):2352-2363. PMID: 32796082
Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), statins, which are used to prevent cardiovascular diseases, are associated with a modest increase in the risk of new-onset diabetes. To investigate the role of...
8.
Yamamuro D, Yamazaki H, Osuga J, Okada K, Wakabayashi T, Takei A, et al.
J Lipid Res . 2020 Jun; 61(9):1287-1299. PMID: 32561542
The acyltransferase LCAT mediates FA esterification of plasma cholesterol. In vitro studies have shown that LCAT also FA-esterifies several oxysterols, but in vivo evidence is lacking. Here, we measured both...
9.
Yamamuro D, Takahashi M, Nagashima S, Wakabayashi T, Yamazaki H, Takei A, et al.
PLoS One . 2020 Jun; 15(6):e0234439. PMID: 32530967
Disturbance of circadian rhythms underlies various metabolic diseases. Constant light exposure (LL) is known to disrupt both central and peripheral circadian rhythms. Here, we attempted to determine whether the effects...
10.
Takei A, Nagashima S, Takei S, Yamamuro D, Murakami A, Wakabayashi T, et al.
Diabetes . 2019 Nov; 69(2):158-164. PMID: 31690648
Adipose tissue macrophages (ATMs) are involved in the development of insulin resistance in obesity. We have recently shown that myeloid cell-specific reduction of HMG-CoA reductase ( ), which is the...