Mahfoud Assem
Overview
Explore the profile of Mahfoud Assem including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
524
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0
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Recent Articles
1.
Assem M, Broeckel U, MacKinnon G
Am J Pharm Educ
. 2021 Jul;
85(4):8249.
PMID: 34283790
Pharmacogenomics, a key tool in personalized medicine, and therapeutic drug management is projected to become an integral part of pharmacy practice. This study describes an innovative pedagogy that used several...
2.
Dhamankar V, Assem M, Donovan M
Inhal Toxicol
. 2015 Nov;
27(14):767-77.
PMID: 26572092
Despite tremendous advancement in the characterization of nasal enzyme expression, knowledge of the role of the nasal mucosa in the metabolism of xenobiotics is still inadequate, primarily due to the...
3.
Al-Ghabeish M, Scheetz T, Assem M, Donovan M
Mol Pharm
. 2015 Jun;
12(8):2742-54.
PMID: 26106909
Mice and rats are commonly used to investigate in vivo nasal drug absorption, yet their small nasal cavities limit their use for in vitro investigations. Bovine tissue explants have been...
4.
Alqudah M, Agarwal S, Al-Keilani M, Sibenaller Z, Ryken T, Assem M
PLoS One
. 2013 Oct;
8(10):e77299.
PMID: 24143218
Using a GWA analysis of a comprehensive glioma specimen population, we identified whole gain of chromosome 19 as one of the major chromosomal aberrations that correlates to patients' outcomes. Our...
5.
Agarwal S, Al-Keilani M, Alqudah M, Sibenaller Z, Ryken T, Assem M
PLoS One
. 2013 May;
8(5):e62852.
PMID: 23696788
Poor prognosis and resistance to therapy in malignant gliomas is mainly due to the highly dispersive nature of glioma cells. This dispersive characteristic results from genetic alterations in key regulators...
6.
Assem M, Sibenaller Z, Agarwal S, Al-Keilani M, Alqudah M, Ryken T
OMICS
. 2012 Mar;
16(3):113-22.
PMID: 22401657
Malignant gliomas are the most frequent type of primary brain tumors. Patients' outcome has not improved despite new therapeutics, thus underscoring the need for a better understanding of their genetics...
7.
Sberna A, Assem M, Xiao R, Ayers S, Gautier T, Guiu B, et al.
Arterioscler Thromb Vasc Biol
. 2011 Jul;
31(10):2232-9.
PMID: 21778422
Objective: The goal of this study was to determine the impact of the nuclear receptor constitutive androstane receptor (CAR) on lipoprotein metabolism and atherosclerosis in hyperlipidemic mice. Methods And Results:...
8.
Sberna A, Assem M, Gautier T, Grober J, Guiu B, Jeannin A, et al.
J Hepatol
. 2010 Dec;
55(1):154-61.
PMID: 21145854
Background & Aims: The constitutive androstane receptor (CAR) is a nuclear receptor expressed in the liver and involved in xenobiotic metabolism. The aim of this study was to assess whether...
9.
Lin Y, Yasuda K, Assem M, Cline C, Barber J, Li C, et al.
Drug Metab Dispos
. 2009 Mar;
37(6):1295-304.
PMID: 19251824
The pregnane X receptor (PXR; PXR.1) can be activated by structurally diverse lipophilic ligands. PXR.2, an alternatively spliced form of PXR, lacks 111 nucleotides encoding 37 amino acids in the...
10.
Pottier N, Yang W, Assem M, Panetta J, Pei D, Paugh S, et al.
J Natl Cancer Inst
. 2008 Dec;
100(24):1792-803.
PMID: 19066270
Background: Glucocorticoids are used in the curative treatment of acute lymphoblastic leukemia (ALL). Resistance to glucocorticoids is an important adverse prognostic factor in newly diagnosed ALL patients but its mechanism...