M Wartmann
Overview
Explore the profile of M Wartmann including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
950
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
OReilly T, Wartmann M, Maira S, Hattenberger M, Vaxelaire J, Muller M, et al.
Cancer Chemother Pharmacol
. 2005 Feb;
55(4):307-317.
PMID: 15723258
Purpose: The microtubule-stabilizing agent patupilone (epothilone B, EPO906) and the tyrosine kinase inhibitor imatinib (STI571, Glivec) which primarily inhibits Bcr-Abl, PDGF and c-Kit tyrosine kinase receptors, were combined in vivo...
2.
Wartmann M, Altmann K
Curr Med Chem Anticancer Agents
. 2003 Apr;
2(1):123-48.
PMID: 12678754
Epothilones are naturally occurring 16-membered macrolides with the ability to promote tubulin polymerization in vitro and to stabilize preformed microtubules against Ca(2+)- or cold-induced depolymerization. At the cellular level, interference...
3.
Sinha S, Sun J, Wartmann M, Lerner R
Chembiochem
. 2002 Feb;
2(9):656-65.
PMID: 11828502
Three monoclonal aldolase antibodies (84G3, 85H6, and 93F3), generated against a beta-diketone hapten (II) by the reactive immunization technique, catalyzed highly enantioselective retro-aldol reactions of the racemic thiazole aldols 13-20....
4.
Schinzer D, Altmann K, Stuhlmann F, Bauer A, Wartmann M
Chembiochem
. 2002 Feb;
1(1):67-70.
PMID: 11828400
No abstract available.
5.
Nicolaou K, Namoto K, Ritzen A, Ulven T, Shoji M, Li J, et al.
J Am Chem Soc
. 2001 Sep;
123(38):9313-23.
PMID: 11562214
The design, chemical synthesis, and biological evaluation of a series of cyclopropyl and cyclobutyl epothilone analogues (3-12, Figure 1) are described. The synthetic strategies toward these epothilones involved a Nozaki-Hiyama-Kishi...
6.
White J, Carter R, Sundermann K, Wartmann M
J Am Chem Soc
. 2001 Jun;
123(23):5407-13.
PMID: 11389619
The phosphonium salt 35, representing one of the two principal subunits of the epothilones, was prepared from propargyl alcohol via heptenone 22. A Wittig reaction of the phosphorane from 35...
7.
Sinha S, Sun J, Miller G, Wartmann M, Lerner R
Chemistry
. 2001 May;
7(8):1691-702.
PMID: 11349910
Naturally occurring epothilones have been synthesized starting from enantiomerically pure aldol compounds 9-11, which were obtained by antibody catalysis. Aldolase antibody 38C2 catalyzed the resolution of (+/-)-9 by enantioselective retro-aldol...
8.
Altmann K, Bold G, Caravatti G, Florsheimer A, Guagnano V, Wartmann M
Bioorg Med Chem Lett
. 2001 Jan;
10(24):2765-8.
PMID: 11133086
A series of new epothilone B and D analogues incorporating fused hetero-aromatic side chains have been prepared. The synthetic strategy is based on olefin 3 as the common intermediate and...
9.
Nicolaou K, Scarpelli R, Bollbuck B, Werschkun B, Pereira M, Wartmann M, et al.
Chem Biol
. 2000 Oct;
7(8):593-9.
PMID: 11048950
Background: Numerous analogs of the antitumor agents epothilones A and B have been synthesized in search of better pharmacological profiles. Insights into the structure-activity relationships within the epothilone family are...
10.
Altmann K, Wartmann M, OReilly T
Biochim Biophys Acta
. 2000 May;
1470(3):M79-91.
PMID: 10799747
No abstract available.