M G von Herrath
Overview
Explore the profile of M G von Herrath including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
1197
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Recent Articles
1.
von Herrath M, Korsgren O, Atkinson M
Clin Exp Immunol
. 2015 May;
183(1):1-7.
PMID: 25989477
Type 1 diabetes (T1D) is one of the most common and severe chronic diseases affecting both children and adults. The aetiology of the disease remains unknown, and thus far no...
2.
Campbell-Thompson M, Atkinson M, Butler A, Chapman N, Frisk G, Gianani R, et al.
Diabetologia
. 2013 Sep;
56(11):2541-3.
PMID: 24006089
No abstract available.
3.
Schneider D, Kretowicz A, von Herrath M
Diabetes Obes Metab
. 2012 Dec;
15(7):581-92.
PMID: 23194064
In type 1 diabetes (T1D) the immune system attacks insulin-producing pancreatic β-cells. Unfortunately, our ability to curb this pathogenic autoimmune response in a disease- and organ-specific manner is still very...
4.
Coppieters K, Wiberg A, Tracy S, von Herrath M
Clin Exp Immunol
. 2012 Mar;
168(1):5-11.
PMID: 22385231
Convincing evidence now indicates that viruses are associated with type 1 diabetes (T1D) development and progression. Human enteroviruses (HEV) have emerged as prime suspects, based on detection frequencies around clinical...
5.
Coppieters K, Amirian N, von Herrath M
Clin Exp Immunol
. 2011 May;
165(2):155-62.
PMID: 21605113
Apoptosis is known as a major mechanism which contributes to beta cell decay in type 1 diabetes. Commitment to this pathway generally involves caspase-mediated protein cleavage and was found to...
6.
Bresson D, von Herrath M
Clin Exp Immunol
. 2011 Jan;
163(3):375-80.
PMID: 21235534
Immune modulators such as anti-thymoglobulin (ATG) are under clinical evaluation for the treatment of type 1 diabetes (T1D). Although such agents have cured T1D in the non-obese diabetic (NOD) model,...
7.
Filippi C, von Herrath M
Clin Exp Immunol
. 2010 Apr;
160(1):113-9.
PMID: 20415860
Based on studies in animal models, viral infections, in particular by enteroviruses, can accelerate or halt type 1 diabetes (T1D) development. Among factors that determine the outcome are the degree...
8.
Van Belle T, Taylor P, von Herrath M
Drug Discov Today Dis Models
. 2010 Apr;
6(2):41-45.
PMID: 20407588
Our understanding of the genetics, aetiology and pathogenesis of Type 1 Diabetes (T1D) was propelled by the discovery of animal models of T1D in the late 1970s and early 1980s,...
9.
Filippi C, von Herrath M
J Pathol
. 2007 Dec;
214(2):224-30.
PMID: 18161757
Chronic viral infections pose serious health concerns, as secondary complications such as immunodeficiencies and cancers are common. Treating such infections with conventional vaccine approaches has proved to be difficult. Studies...
10.
Petersen J, Bregenholt S, Apostolopolous V, Homann D, Wolfe T, Hughes A, et al.
Clin Exp Immunol
. 2003 Sep;
134(1):38-45.
PMID: 12974752
Our earlier investigations have demonstrated a critical difference in the efficacy of orally administered porcine compared to human or mouse insulin (no effect) in preventing type I diabetes in two...