Luke L McGoldrick
Overview
Explore the profile of Luke L McGoldrick including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
569
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0
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Recent Articles
11.
Singh A, McGoldrick L, Twomey E, Sobolevsky A
Sci Adv
. 2018 Aug;
4(8):eaau6088.
PMID: 30116787
Calcium (Ca) plays a major role in numerous physiological processes. Ca homeostasis is tightly controlled by ion channels, the aberrant regulation of which results in various diseases including cancers. Calmodulin...
12.
Singh A, Saotome K, McGoldrick L, Sobolevsky A
Nat Commun
. 2018 Jun;
9(1):2465.
PMID: 29941865
Transient receptor potential (TRP) channels are involved in various physiological processes, including sensory transduction. The TRP channel TRPV6 mediates calcium uptake in epithelia and its expression is dramatically increased in...
13.
Singh A, McGoldrick L, Saotome K, Sobolevsky A
Channels (Austin)
. 2018 Mar;
12(1):137-152.
PMID: 29589513
Transient receptor potential (TRP) ion channels are molecular sensors of a large variety of stimuli including temperature, mechanical stress, voltage, small molecules including capsaicin and menthol, and lipids such as...
14.
McGoldrick L, Singh A, Saotome K, Yelshanskaya M, Twomey E, Grassucci R, et al.
Nature
. 2017 Dec;
553(7687):233-237.
PMID: 29258289
Calcium-selective transient receptor potential vanilloid subfamily member 6 (TRPV6) channels play a critical role in calcium uptake in epithelial tissues. Altered TRPV6 expression is associated with a variety of human...
15.
Park J, Thorsness M, Policastro R, McGoldrick L, Hollingsworth N, Thorsness P, et al.
Mol Biol Cell
. 2016 Jun;
27(15):2435-49.
PMID: 27280386
The Vps13 protein family is highly conserved in eukaryotic cells. Mutations in human VPS13 genes result in a variety of diseases, such as chorea acanthocytosis (ChAc), but the cellular functions...