Luke A ONeill
Overview
Explore the profile of Luke A ONeill including associated specialties, affiliations and a list of published articles.
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56
Citations
7544
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Recent Articles
1.
Kurmasheva N, Said A, Wong B, Kinderman P, Han X, Rahimic A, et al.
Nat Commun
. 2024 Dec;
15(1):10698.
PMID: 39702301
No abstract available.
2.
Kurmasheva N, Said A, Wong B, Kinderman P, Han X, Rahimic A, et al.
Nat Commun
. 2024 May;
15(1):4096.
PMID: 38750019
The presence of heterogeneity in responses to oncolytic virotherapy poses a barrier to clinical effectiveness, as resistance to this treatment can occur through the inhibition of viral spread within the...
3.
Baldanti F, Ganguly N, Wang G, Mockel M, ONeill L, Renz H, et al.
Crit Rev Clin Lab Sci
. 2022 Mar;
59(7):445-459.
PMID: 35289222
A plethora of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic tests are available, each with different performance specifications, detection methods, and targets. This narrative review aims to summarize the...
4.
Williams N, Ryan D, Costa A, Mills E, Jedrychowski M, Cloonan S, et al.
J Biol Chem
. 2021 Dec;
298(2):101501.
PMID: 34929172
Activated macrophages undergo metabolic reprogramming, which not only supports their energetic demands but also allows for the production of specific metabolites that function as signaling molecules. Several Krebs cycles, or...
5.
Buckley C, Chernajovsky L, Chernajovsky Y, Modis L, ONeill L, Brown D, et al.
Nat Immunol
. 2021 Oct;
22(11):1344-1348.
PMID: 34675389
No abstract available.
6.
Netea M, Balkwill F, Chonchol M, Cominelli F, Donath M, Giamarellos-Bourboulis E, et al.
Nat Immunol
. 2020 Dec;
22(2):254.
PMID: 33288963
No abstract available.
7.
Phelan J, McQuaid K, Kenny C, Gogan K, Cox D, Basdeo S, et al.
Front Immunol
. 2020 Jun;
11:836.
PMID: 32477344
Tuberculosis is the single biggest infectious killer in the world and presents a major global health challenge. Antimicrobial therapy requires many months of multiple drugs and incidences of drug resistant...
8.
Williams N, ONeill L
Trends Immunol
. 2020 Jan;
41(2):93-94.
PMID: 31948874
Metabolic reprogramming in macrophages supports effector functions and differs depending on the activating stimulus. Lauterbach et al. now show that early metabolic alterations in macrophages driven by LPS signaling serve...
9.
McElvaney O, Zaslona Z, Becker-Flegler K, Palsson-McDermott E, Boland F, Gunaratnam C, et al.
Am J Respir Crit Care Med
. 2019 Aug;
200(11):1381-1391.
PMID: 31454256
Cystic fibrosis (CF) pulmonary disease is characterized by chronic infection with and sustained neutrophil-dominant inflammation. The lack of effective antiinflammatory therapies for people with CF (PWCF) represents a significant challenge....
10.
Ryan D, Murphy M, Frezza C, Prag H, Chouchani E, ONeill L, et al.
Nat Metab
. 2019 Apr;
1:16-33.
PMID: 31032474
Metabolic reprogramming has become a key focus for both immunologists and cancer biologists, with exciting advances providing new insights into underlying mechanisms of disease. Metabolites traditionally associated with bioenergetics or...